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首页> 外文期刊>Anticancer Research: International Journal of Cancer Research and Treatment >Forsen psychological risk inventory for breast cancer patients: a prospective case-control study with special reference to the use of psychiatric medications.
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Forsen psychological risk inventory for breast cancer patients: a prospective case-control study with special reference to the use of psychiatric medications.

机译：乳腺癌患者的前瞻性心理风险清单：一项前瞻性病例对照研究，特别提到了精神科药物的使用。

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BACKGROUND: In 1989, Forsen introduced an inventory for psychological identification of breast cancer (BC) patients before biopsy. The associations between the Forsen inventory (FI) and the risk of BC are rarely considered together in a prospective study. PATIENTS AND METHODS: In an extension of the Kuopio Breast Cancer Study, 115 women with breast symptoms were semi-structurally interviewed in-depth and asked to complete standardised questionnaires (Beck, Forsen and Spielberger) and all study variables were obtained before any diagnostic procedures were carried out. The Montgomery-Asberg depression rating scale (MADRS) was used to evaluate the depression of the study participants. RESULTS: The clinical examination and biopsy showed BC in 34 patients, benign breast disease (BBD) in 53 patients and 28 individuals were shown to be healthy (HSS). The BC group had more severe anxiety during a two-year prodromal period (4/34 patients, 11.8%) than the BBD (3/53 patients, 5.7%) and HSS groups (1/28 patients, 3.6%). The mean sum of the scores of the FI variables during a six-year prodromal period were significantly lower in the BC group (9.8) than in the BBD (11.8) and HSS groups (12.5). In addition, the women in the BC group tended to use more psychiatric medication during a six-year prodromal period (7/34 patients, 20.6%) than the patients in the BBD (7/53, 13.2%) and HSS groups (3/28, 10.7%). CONCLUSION: The results of this study support a very weak association between the FI and BC risk. However, the number of cases with psychiatric medications was insufficient to support statistically a specific link between psychiatric medications and increased BC risk.
机译：背景：1989年，Forsen提出了一份活检前对乳腺癌（BC）患者进行心理识别的清单。在前瞻性研究中，很少同时考虑Forsen清单（FI）和BC风险之间的关联。患者和方法：在Kuopio乳腺癌研究的一项扩展研究中，对115名患有乳腺症状的妇女进行了半结构化的深入访谈，并要求他们完成标准化的问卷（Beck，Forsen和Spielberger），所有研究变量均在进行任何诊断程序之前获得被执行。使用蒙哥马利-阿斯伯格抑郁量表（MADRS）评估研究参与者的抑郁程度。结果：临床检查和活检显示34例为BC，53例为良性乳腺疾病（BBD），其中28例表现为健康（HSS）。 BC组在两年的前驱期间（4/34例，11.8％）比BBD（3/53例，5.7％）和HSS组（1/28例，3.6％）更严重。六年前驱期的FI变量平均得分在BC组（9.8）明显低于BBD（11.8）和HSS组（12.5）。此外，BC组女性在前驱六年中倾向于使用更多的精神科药物（7/34患者，占20.6％），而BBD组（7 / 53，13.2％）和HSS组（3 / 28，10.7％）。结论：本研究结果支持FI和BC风险之间的关联非常弱。但是，接受精神科药物治疗的病例数量不足以统计地支持精神科药物与BC风险增加之间的特定联系。

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