Structure of the recombinant antibody Fab fragment f3p4.

Frey D; Huber T; Pluckthun AGrutter MG

首页> 外文期刊>Acta crystallographica.Section D. Biological crystallography >Structure of the recombinant antibody Fab fragment f3p4.

【24h】

Structure of the recombinant antibody Fab fragment f3p4.

机译：结构的重组抗体Fab片段f3p4。

获取原文

获取原文并翻译 | 示例

掌桥外文数据库（机构版） >>

开具论文收录证明 >>

文献代查 >>

页面导航

摘要
著录项
相似文献
相关主题

摘要

The structure of the antibody Fab fragment f3p4, which was selected from a subset of the synthetic HuCAL antibody library to bind the sodium citrate symporter CitS, is described at 1.92 A resolution. Comparison with computational models revealed deviations in a few framework positions and in the binding loops. The crystals belong to space group P2(1)2(1)2 and contain four molecules in the asymmetric unit, with unit-cell parameters a=102.77, b=185.92, c=102.97 A. These particular unit-cell parameters allowed pseudo-merohedral twinning; interestingly, the twinning law relates a twofold screw axis to a twofold axis.

机译：抗体Fab片段f3p4的结构,这是选自合成的一个子集HuCAL抗体库绑定柠檬酸钠同向转运国旅,被描述为1.92 A决议。显示位置偏差在几个框架在绑定循环。空间群P2(1) 2(1) 2,包含四个分子在不对称单位晶胞参数= 102.77, b = 185.92, c = 102.97。晶胞参数允许pseudo-merohedral双晶;一个双重的螺旋轴两个轴。

著录项

来源
《Acta crystallographica.Section D. Biological crystallography》 |2008年第6期|636-643|共8页
作者
Frey D; Huber T; Pluckthun AGrutter MG;
展开▼
作者单位

Department of Biochemistry, University of Zurich, Switzerland.;

展开▼
收录信息
原文格式 PDF
正文语种英语
中图分类化学;
关键词
Computational modeling; Complementarity Determining Regions; Recombinant AntibodyImmunoglobulin Fab FragmentsCrystallographyBinding SitesX-rays;

机译：计算模型;互补决定FragmentsCrystallographyBinding SitesX-rays;

相似文献

外文文献
中文文献
专利

1. ANTITUMOR EFFECTS OF MONOCLONAL ANTIBODY FAB′ FRAGMENT CONTAINING IMMUNOCONJUGATES [J] . 刘小云, 甄永苏中国医学科学杂志（英文版） . 2002,第001期
2. PRODUCTION OF PHAGE-DISPLAYED ANTI-IDIOTYPIC ANTIBODY SINGLE CHAIN VARIABLE FRAGMENTS TO MG7 MONOCLONAL ANTIBODY DIRECTED AGAINST GASTRIC CARCINOMA [J] . 何凤田, 聂勇战, 陈宝军, 中国医学科学杂志（英文版） . 2002,第004期
3. 『テクラ·ユーザーデイ2011」東京--テクラ「Tekla Structures 17」を披露--GC、ファブのBIM担当者らが参加 [J] . 鉄構技術 . 2011,第6a277期

机译：“Tecara 2011年用户第2011年”Tokyo-Tekla Structures 17提供Tekla Structures 17-GC，BIM负责FABS参加
4. Generation of Fab fragment-like molecular recognition proteins against staphylococcal enterotoxin B by phage display technology. [J] . Urushibata Y, Itoh K, Ohshima MSeto Y Clinical and vaccine immunology: CVI . 2010,第11期

机译：代的Fab fragment-like分子识别蛋白质对葡萄球菌肠毒素B通过噬菌体展示技术。
5. Crystal structures of an enantioselective fab-fragment in free and complex forms [J] . Parkkinen T, Nevanen TK, Koivula A, Journal of Molecular Biology . 2006,第2期

机译：自由和复杂形式的对映选择性fab-fragment的晶体结构
6. Effective Translation of LTL to Deterministic Rabin Automata: Beyond the (F,G)-Fragment [C] . Tomas Babiak, Frantisek Blahoudek, Mojmir Kretinsky, International Symposium on Automated Technology for Verification and Analysis . 2013

机译：有效翻译LTL以确定性Rabin Automata：超越（F，G）-Fragment
7. Rites of identity and stages of postcolonial consciousness in Richard Wright's "Native Son" and Ayi Kwei Armah's "Fragments". [D] . Diouf, Waly. 2007

机译：理查德·赖特（Richard Wright）的“原住民儿子”（Native Son）和阿依奎阿玛（Ayi Kwei Armah）的“片段”（Fragments）中的身份认同和后殖民意识阶段。
8. STRUCTURE PLOT: a program for drawing elegant STRUCTURE bar plots in user friendly interface [O] . Ramesh Krishnan Ramasamy, Sumathy Ramasamy, Bharat Bushan Bindroo, -1

机译：STRUCTURE PLOT：用于在用户友好的界面中绘制精美的STRUCTURE条形图的程序
9. P152 LACK OF PLACENTAL TRANSFER AND ACCUMULATION IN MILK OF AN ANTI-TNF PEGYLATED FAB'FRAGMENT IN RATS [O] . S. Stephens, D. Brown, A. Nesbitt, 2007

机译：P152缺乏胎盘转移和牛奶中的抗TNF Pegymated Fab'Fragment的积累
10. S-Fab Balloon Flights: Experimental Balloons Fabricated with S-Fab Polypropylene Tri-Laminate Film. [R] . Cox, D. W. 1966

机译：s-Fab气球航班：用s-Fab聚丙烯三层薄膜制造的实验气球。

Structure of the recombinant antibody Fab fragment f3p4.

摘要

著录项

相似文献

相关主题

期刊订阅