Candida albicans infections in renal transplant recipients: effect of caspofungin on polymorphonuclear cells.

Allizond V; Banche G; Giacchino F; Merlino C; Scalas D; Tullio V; Garneri G; Mandras N; Roana J; Cuffini AM

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Candida albicans infections in renal transplant recipients: effect of caspofungin on polymorphonuclear cells.

机译：肾移植受者中的白色念珠菌感染：卡泊芬净对多形核细胞的影响。

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This study aimed to compare the caspofungin immunomodulating activities against Candida albicans on polymorphonuclear cells (PMNs) from renal transplant recipients (RTRs) and healthy subjects (HSs). RTR PMNs showed a significantly reduced fungicidal activity compared with that of HS PMNs. Addition of caspofungin to RTR PMNs significantly potentiated the yeast intracellular killing rate, achieving values similar to those observed for HS PMNs. These data show that caspofungin is suitable for invasive candidiasis treatment in patients with immune system-impaired components.

机译：这项研究旨在比较来自肾移植受者（RTR）和健康受试者（HS）的多形核细胞（PMN）对白色念珠菌的卡泊芬净的免疫调节活性。与HS PMN相比，RTR PMN的杀真菌活性明显降低。在RTR PMN中添加卡泊芬净可显着增强酵母细胞内杀伤率，其值与HS PMN相似。这些数据表明卡泊芬净适用于免疫系统受损的患者的侵袭性念珠菌病治疗。

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《Antimicrobial agents and chemotherapy.》 |2011年第12期|共3页
作者
Allizond V; Banche G; Giacchino F; Merlino C; Scalas D; Tullio V; Garneri G; Mandras N; Roana J; Cuffini AM;
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正文语种 eng
中图分类治疗学;
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1. Candida albicans infections in renal transplant recipients: effect of caspofungin on polymorphonuclear cells. [J] . Allizond V, Banche G, Giacchino F, Antimicrobial agents and chemotherapy. . 2011,第12期

机译：肾移植受者中的白色念珠菌感染：卡泊芬净对多形核细胞的影响。
2. Molecular monitoring of Candida albicans infections in liver transplant recipients. [J] . Tavanti A, Lupetti A, Ghelardi E, European journal of clinical microbiology and infectious diseases: Official publication of the European Society of Clinical Microbiology . 2001,第8期

机译：肝移植受者中白色念珠菌感染的分子监测。
3. A retrospective analysis of the use of caspofungin in recipients of liver transplant with a modified high index of suspicion for fungal infection. A critical review of mortality, acute cellular rejection, infections, and changes in the liver function tests while on caspofungin. [J] . Doria C, Bodzin AS, Vaccino S, Clinical transplantation. . 2011,第4期

机译：对卡泊芬净在肝移植受者中的使用进行回顾性分析，该患者对真菌感染的怀疑度较高。对使用卡泊芬净进行治疗时的死亡率，急性细胞排斥反应，感染以及肝功能测试的变化进行了严格的审查。
4. Phagocytosis and killing activity of human polymorphonuclear cells against two different forms of candida albicans, conidia and hyphae [C] . D.Takeda, N.Shimono, U.Uchida, Proceedings of the Fourth China-Jpan international congress of mycology . 1998

机译：人类多形核细胞对两种不同形式的白色念珠菌分生孢子和菌丝的吞噬作用和杀伤活性
5. Protein Engineering Approaches to Improve the Therapeutic Potential of Histatin-5 for Candida albicans Infections [D] . Leissa, Jesse Alton. 2019

机译：蛋白质工程方法，提高组织蛋白-5的治疗潜力，用于念珠菌肽肽感染
6. Candida albicans Infections in Renal Transplant Recipients: Effect of Caspofungin on Polymorphonuclear Cells [O] . Valeria Allizond, Giuliana Banche, Franca Giacchino, 2011

机译：念珠菌感染肾移植受者：卡泊芬净对多形核细胞的影响。
7. Candida albicans Infections in Renal Transplant Recipients: Effect of Caspofungin on Polymorphonuclear Cells ▿ [O] . Allizond, Valeria, Banche, Giuliana, Giacchino, Franca, 2011

机译：念珠菌感染肾移植受者：卡泊芬净对多形核细胞的影响。 ▿

Candida albicans infections in renal transplant recipients: effect of caspofungin on polymorphonuclear cells.

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