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Biguanide-Atovaquone Synergy against Plasmodium falciparum In Vitro.

机译:对抗恶性疟原虫的双胍-阿托伐醌协同作用。

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摘要

The synergistic potential of a range of biguanides, their triazine metabolites, tetracyclines, and pyrimethamine in combination with atovaquone has been assessed. All five biguanides tested interacted synergistically with atovaquone against Plasmodium falciparum in vitro. All of the other compounds tested were either additive or antagonistic.
机译:已评估了多种双胍类,其三嗪代谢物,四环素和乙胺嘧啶与阿托伐醌的协同潜力。在体外测试的所有五种双胍类药物均与阿托伐醌协同对抗恶性疟原虫。测试的所有其他化合物均为加性或拮抗性。

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