Synergistic activities of macrolide antibiotics against Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia, and Alcaligenes xylosoxidans isolated from patients with cystic fibrosis.

Saiman Lisa; Chen Yunhua; Gabriel PabloSan; Knirsch Charles

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Synergistic activities of macrolide antibiotics against Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia, and Alcaligenes xylosoxidans isolated from patients with cystic fibrosis.

机译：大环内酯类抗生素对铜绿假单胞菌，洋葱伯克霍尔德菌，嗜麦芽窄食单胞菌和从囊性纤维化患者分离的产木素氧化酶的协同作用。

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Azithromycin and clarithromycin were paired with other antibiotics to test synergistic activity against 300 multidrug-resistant pathogens isolated from cystic fibrosis (CF) patients. Clarithromycin-tobramycin was most active against Pseudomonas aeruginosa and inhibited 58% of strains. Azithromycin-trimethoprim-sulfamethoxazole, azithromycin-ceftazidime, and azithromycin-doxycycline or azithromycin-trimethoprim-sulfamethoxazole inhibited 40, 20, and 22% of Stenotrophomonas maltophilia, Burkholderia cepacia complex, and Achromobacter (Alcaligenes) xylosoxidans strains, respectively.

机译：将阿奇霉素和克拉霉素与其他抗生素配对以测试针对从囊性纤维化（CF）患者中分离出来的300种多药耐药病原体的协同活性。克拉霉素-妥布霉素对铜绿假单胞菌最有效，可抑制58％的菌株。阿奇霉素-甲氧苄啶-磺胺甲恶唑，阿奇霉素-头孢他啶和阿奇霉素-强力霉素或阿奇霉素-甲氧苄啶-磺胺甲恶唑分别抑制嗜麦芽窄食单胞菌，嗜酸伯克霍尔德氏菌复合体和无色杆菌的40％，20％和22％。

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来源
《Antimicrobial agents and chemotherapy.》 |2002年第4期|共3页
作者
Saiman Lisa; Chen Yunhua; Gabriel PabloSan; Knirsch Charles;
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正文语种 eng
中图分类治疗学;
关键词
Alcaligenes; Antibiotics; Macrolide; Burkholderia cepacia; Cystic Fibrosis; 产碱菌属; 抗生素; 大环内酯; 伯霍尔德氏杆菌; 洋葱; 囊性纤维变性; 假单胞菌; 铜绿;

机译：Alcaligenes;Antibiotics;Macrolide;Burkholderia cepacia;Cystic Fibrosis;产碱菌属;抗生素;大环内酯;伯霍尔德氏杆菌;洋葱;囊性纤维变性;假单胞菌;铜绿;

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1. Synergistic activities of macrolide antibiotics against Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia, and Alcaligenes xylosoxidans isolated from patients with cystic fibrosis. [J] . Saiman Lisa, Chen Yunhua, Gabriel PabloSan, Antimicrobial agents and chemotherapy. . 2002,第4期

机译：大环内酯类抗生素对铜绿假单胞菌，洋葱伯克霍尔德菌，嗜麦芽窄食单胞菌和从囊性纤维化患者分离的产木素氧化酶的协同作用。
2. Combination antibiotic susceptibility of biofilm-grown Burkholderia cepacia and Pseudomonas aeruginosa isolated from patients with pulmonary exacerbations of cystic fibrosis. [J] . Dales L, Ferris W, Vandemheen K European journal of clinical microbiology and infectious diseases: Official publication of the European Society of Clinical Microbiology . 2009,第10期

机译：从肺囊性纤维化病情加重的患者中分离出生物膜生长的洋葱伯克霍尔德菌和铜绿假单胞菌的联合抗生素敏感性。
3. Identification of Pseudomonas aeruginosa, Burkholderia cepacia complex, and Stenotrophomonas maltophilia in respiratory samples from cystic fibrosis patients using multiplex PCR. [J] . da Silva Filho LV, Tateno AF, Velloso Lde F, Pediatric Pulmonology . 2004,第6期

机译：使用多重PCR鉴定囊性纤维化患者呼吸道样品中的铜绿假单胞菌，洋葱伯克霍尔德菌复合体和嗜麦芽窄食单胞菌。
4. OMICS approaches to reveal Burkholderia cenocepacia adaptive strategies to long-term residence in the lungs of cystic fibrosis patients under antibiotic therapy [C] . Madeira Andreia, Mira Nuno P, Santos Pedro M, 1st Portuguese Meeting in Bioengineering . 2011

机译：OMICS方法揭示在抗生素治疗下囊性纤维化患者长期驻留在肺泡中的伯克霍尔德菌种的适应策略
5. Comparison of aspartate transcarbamoylase activity between Pseudomonas aeruginosa which has one chromosome and Burkholderia cepacia which has three chromosomes. [D] . Nusair, Arwa Y. 2012

机译：具有一条染色体的铜绿假单胞菌和具有三条染色体的洋葱伯克霍尔德菌的天冬氨酸转氨甲酰酶活性的比较。
6. Synergistic Activities of Macrolide Antibiotics against Pseudomonas aeruginosa Burkholderia cepacia Stenotrophomonas maltophilia and Alcaligenes xylosoxidans Isolated from Patients with Cystic Fibrosis [O] . Lisa Saiman, Yunhua Chen, Pablo San Gabriel, 2002

机译：大环内酯类抗生素对铜绿假单胞菌洋葱伯克霍尔德菌嗜麦芽单胞菌嗜麦芽窄食单胞菌和囊性纤维化患者分离的产木素氧化木聚糖的协同活性。
7. Synergistic Activities of Macrolide Antibiotics against Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia, and Alcaligenes xylosoxidans Isolated from Patients with Cystic Fibrosis [O] . Saiman, Lisa, Chen, Yunhua, San Gabriel, Pablo, 2002

机译：大环内酯类抗生素对铜绿假单胞菌，洋葱伯克霍尔德菌，嗜麦芽单胞菌，嗜麦芽窄食单胞菌和囊性纤维化患者分离的产木素氧化酶的协同作用

Synergistic activities of macrolide antibiotics against Pseudomonas aeruginosa, Burkholderia cepacia, Stenotrophomonas maltophilia, and Alcaligenes xylosoxidans isolated from patients with cystic fibrosis.

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