Heterologous production of albicidin: a promising approach to overproducing and characterizing this potent inhibitor of DNA gyrase.

Vivien E; Pitorre D; Cociancich S; Pieretti I; Gabriel DW; Rott PC; Royer M

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Heterologous production of albicidin: a promising approach to overproducing and characterizing this potent inhibitor of DNA gyrase.

机译：异种杀菌素的异源生产：过量生产和表征这种有效的DNA旋转酶抑制剂的有前途的方法。

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The phytotoxin and polyketide antibiotic albicidin produced by Xanthomonas albilineans is a highly potent DNA gyrase inhibitor. Low yields of albicidin production have slowed studies of its chemical structure. Heterologous expression of albicidin biosynthetic genes in X. axonopodis pv. vesicatoria resulted in a sixfold increase in albicidin production, offering promising strategies for engineering overproduction.

机译：Xanthomonas albilineans生产的植物毒素和聚酮类抗生素杀菌素是一种高效的DNA旋转酶抑制剂。白屈菜素生产的低产量减慢了其化学结构的研究。拟南芥x。axonopodis pv。中的albicidin生物合成基因的异源表达。 vesicatoria使白菊素的产量增加了六倍，为工程过量生产提供了有希望的策略。

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《Antimicrobial agents and chemotherapy.》 |2007年第4期|共4页
作者
Vivien E; Pitorre D; Cociancich S; Pieretti I; Gabriel DW; Rott PC; Royer M;
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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
albicidin; Production; DNA Gyrase; Heterologous;

机译：白lb素;生产;DNA回旋酶;异源;

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1. Heterologous production of albicidin: a promising approach to overproducing and characterizing this potent inhibitor of DNA gyrase. [J] . Vivien E, Pitorre D, Cociancich S, Antimicrobial agents and chemotherapy. . 2007,第4期

机译：异种杀菌素的异源生产：过量生产和表征这种有效的DNA旋转酶抑制剂的有前途的方法。
2. Albicidin, a potent DNA gyrase inhibitor with clinical potential [J] . Hashimi Saeed Mujahid The Journal of Antibiotics: An International Journal . 2019,第11期

机译：白蛋白，具有临床潜力的有效的DNA乙酶抑制剂
3. Discovery of pyrazolthiazoles as novel and potent inhibitors of bacterial gyrase. [J] . Ronkin SM, Badia M, Bellon S, Bioorganic and Medicinal Chemistry Letters . 2010,第9期

机译：发现吡唑并噻唑类是细菌促旋酶的新型有效抑制剂。
4. Multivalent DNA aptamers as potent inhibitors of L-selectin mediated lymphocyte rolling [C] . Jens Dernedde, Sebastian Riese, Konrad Buscher, World biomaterials congress . 2016

机译：多价DNA适体作为L-选择蛋白介导的淋巴细胞滚动的有效抑制剂
5. High Yield Deregulated Plasmid DNA Production in Escherichia coli Characterized by Proteomics and Metabolic Flux Analysis. [D] . Meade, Jonathan W. 2013

机译：蛋白质组学和代谢通量分析表征了大肠杆菌中高产失调的质粒DNA的生产。
6. Heterologous Production of Albicidin: a Promising Approach to Overproducing and Characterizing This Potent Inhibitor of DNA Gyrase [O] . Eric Vivien, Delphine Pitorre, Stéphane Cociancich, 2007

机译：异源阿比西定生产：过量生产和表征这种强力的DNA旋转酶抑制剂的有前途的方法。
7. Heterologous Production of Albicidin: a Promising Approach to Overproducing and Characterizing This Potent Inhibitor of DNA Gyrase▿ [O] . Vivien, Eric, Pitorre, Delphine, Cociancich, Stéphane, 2007

机译：异源阿比西定生产：过量生产和表征这种强力的DNA促旋酶抑制剂的有前途的方法

Heterologous production of albicidin: a promising approach to overproducing and characterizing this potent inhibitor of DNA gyrase.

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