首页> 外文期刊>Antimicrobial agents and chemotherapy. >Antimicrobial Resistance of Campylobacter jejuni subsp. jejuni Strains Isolated from Humans in 1998 to 2001 in Montreal, Canada.
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Antimicrobial Resistance of Campylobacter jejuni subsp. jejuni Strains Isolated from Humans in 1998 to 2001 in Montreal, Canada.

机译:空肠弯曲菌亚种的抗药性。空肠菌株,1998年至2001年在加拿大蒙特利尔与人类隔离。

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摘要

The rates of resistance of 51 to 72 human strains of Campylobacter jejuni subsp. jejuni isolated annually from 1998 to 2001 in Montreal, Quebec, Canada, varied from 1 to 12% for erythromycin, 43 to 68% for tetracycline, and 10 to 47% for ciprofloxacin. In the last years of the study, there was a significant increase in the rate of resistance to ciprofloxacin (P = 0.00003) but not in the rate of resistance to erythromycin (P = 0.056) or tetracycline (P = 0.095) compared to the rate obtained in the first years. All 51 C. jejuni strains isolated in 2001 were susceptible to gentamicin, amoxicillin-clavulanic acid, imipenem, and meropenem. From 1999 to 2001, 74 strains of C. jejuni acquired abroad were significantly more resistant to ciprofloxacin than 109 strains of C. jejuni acquired locally (66 versus 9%, P < 0.00001) but were not significantly more resistant to erythromycin (1 versus 6%, P = 0.15) or to tetracycline (55 versus 58%, P = 0.87).
机译:空肠弯曲菌亚种对51至72株人类菌株的耐药率。从1998年至2001年,每年在加拿大魁北克省蒙特利尔分离出的空肠,红霉素的变化范围为1%至12%,四环素的变化范围为43%至68%,环丙沙星的变化范围为10%至47%。在研究的最后几年中,与环丙沙星的耐药率相比,环丙沙星的耐药率显着增加(P = 0.00003),而对红霉素(P = 0.056)或四环素的耐药率却没有显着增加(P = 0.095)在头几年获得的。 2001年分离出的所有51个空肠弯曲杆菌菌株均对庆大霉素,阿莫西林-克拉维酸,亚胺培南和美罗培南敏感。从1999年到2001年,在国外获得的74株空肠弯曲杆菌对环丙沙星的抵抗力比在本地获得的109株空肠弯曲杆菌(66比9%,P <0.00001),但对红霉素的抵抗力没有明显提高(1对6 %,P = 0.15)或四环素(55对58%,P = 0.87)。

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