In vitro activities of antibiotics alone and in combination against Brucella melitensis at neutral and acidic pHs.

Akova M; Gur D; Livermore DM; Kocagoz T; Akalin HE

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In vitro activities of antibiotics alone and in combination against Brucella melitensis at neutral and acidic pHs.

机译：在中性和酸性pH值下，单独和组合使用抗生素对布鲁氏布鲁氏菌的体外活性。

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Brucellae survive acidic pHs in phagolysosomes. Azithromycin, streptomycin, and quinolones were active against Brucella melitensis at pH 7.0 but not at pH 5.0; rifampin and doxycycline retained activity at pH 5.0. Regardless of pH, azithromycin-rifampin and ofloxacin-rifampin showed less synergy than established streptomycin-doxycycline and rifampin-doxycycline combinations.

机译：布鲁氏菌在吞噬溶酶体中的酸性pH值中存活。阿奇霉素，链霉素和喹诺酮类药物在pH 7.0时对melus布鲁氏菌有活性，但在pH 5.0时则无活性。利福平和强力霉素在pH 5.0时保持活性。无论pH值如何，阿奇霉素-利福平和氧氟沙星-利福平的协同作用均低于链霉素-强力霉素和利福平-强力霉素的组合。

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《Antimicrobial agents and chemotherapy.》 |1999年第5期|共3页
作者
Akova M; Gur D; Livermore DM; Kocagoz T; Akalin HE;
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原文格式 PDF
正文语种 eng
中图分类治疗学;
关键词
Antibiotics; Combined; Azithromycin; Brucella melitensis; Doxycycline; Quinolones; 抗生素类; 复合; 叠氮红霉素; 布氏杆菌; 马尔他; 脱氧土霉素; 喹诺酮类; 利福平;

机译：Antibiotics;Combined;Azithromycin;Brucella melitensis;Doxycycline;Quinolones;抗生素类;复合;叠氮红霉素;布氏杆菌;马尔他;脱氧土霉素;喹诺酮类;利福平;

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1. In vitro activities of antibiotics alone and in combination against Brucella melitensis at neutral and acidic pHs. [J] . Akova M, Gur D, Livermore DM, Antimicrobial agents and chemotherapy. . 1999,第5期

机译：在中性和酸性pH值下，单独和组合使用抗生素对布鲁氏布鲁氏菌的体外活性。
2. Determining in vitro synergistic activities of tigecycline with several other antibiotics against Brucella melitensis using checkerboard and time-kill assays. [J] . Aliskan H, Can F, Demirbilek M Journal of chemotherapy . 2009,第1期

机译：使用棋盘和时间杀灭测定法测定替加环素与其他几种抗生素对布鲁氏菌的协同作用。
3. Comparison of E test to microdilution for determining in vitro activities of antibiotics against Brucella melitensis (letter) [J] . Gur D, Kocagoz S, Akova M, Antimicrobial agents and chemotherapy. . 1999,第9期

机译：E试验与微量稀释法测定抗生素对布鲁氏菌的体外活性的比较（字母）
4. Rapid identification of Yersinia pestis and Brucella melitensis by chip-based continuous flow PCR [C] . Michael Dietzsch, Falk Melzer, Herbert Tomaso, Smart biomedical and physiological sensor technology IX. . 2012

机译：基于芯片的连续流PCR快速鉴定鼠疫耶尔森菌和布鲁氏菌
5. THE PHARMACOLOGICAL ACTIVITY OF THE ACIDIC, BASIC, AND POLAR-NEUTRAL FRACTIONS OF MARIHUANA WHOLE SMOKE CONDENSATE ALONE, AND IN COMBINATION WITH, DELTA-9-TETRAHYDROCANNABINOL [D] . JOHNSON, JAN MOORE 1981

机译：大麻全烟冷凝的酸性，碱性和极性中性馏分的药理活性，以及与DELTA-9-四氢大麻酚的结合
6. Note: In Vitro Activities of Antibiotics Alone and in Combination against Brucella melitensis at Neutral and Acidic pHs [O] . Murat Akova, Deniz Gür, David M. Livermore, 1999

机译：注意：在中性和酸性pH值下单独的抗生素及其结合对布鲁氏布鲁氏菌的体外活性
7. In vitro synergistic activity of antibiotic combinations against Brucella melitensis using E-test methodology Atividade sinergística in vitro de combinações de antibióticos contra Brucella melitensis através da metodologia E-test [O] . Selcuk Kilic, Murat Dizbay, Kenan Hizel, 2008

机译：使用E-测试方法研究抗生素组合对布鲁氏菌的体外协同活性通过E-测试方法体外抗生素组合对布鲁氏菌的协同活性

In vitro activities of antibiotics alone and in combination against Brucella melitensis at neutral and acidic pHs.

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