Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli.

Duval V; Nicoloff H; Levy SB

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Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli.

机译：lon和ycgE的联合失活可通过减少大肠杆菌中OmpF孔蛋白的量来降低多药敏感性。

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Transposon inactivation of ycgE, a gene encoding a putative transcriptional regulator, led to decreased multidrug susceptibility in an Escherichia coli lon mutant. The multidrug susceptibility phenotype (e.g., to tetracycline and beta-lactam antibiotics) required the inactivation of both lon and ycgE. In this mutant, a decreased amount of OmpF porin contributes to the lowered drug susceptibility, with a greater effect at 26 degrees C than at 37 degrees C.

机译：ycgE的转座子失活，该基因编码一个假定的转录调节因子，导致大肠杆菌lon突变体的多药敏感性降低。多药敏感性表型（例如，对四环素和β-内酰胺类抗生素）需要灭活lon和ycgE。在此突变体中，减少的OmpF孔蛋白含量有助于降低药物敏感性，在26摄氏度下的效果大于在37摄氏度下的效果。

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《Antimicrobial agents and chemotherapy.》 |2009年第11期|共5页
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Duval V; Nicoloff H; Levy SB;
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正文语种 eng
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1. Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli. [J] . Duval V, Nicoloff H, Levy SB Antimicrobial agents and chemotherapy. . 2009,第11期

机译：lon和ycgE的联合失活可通过减少大肠杆菌中OmpF孔蛋白的量来降低多药敏感性。
2. A Novel Regulatory Cascade Involving BluR, YcgZ, and Lon Controls the Expression of Escherichia coli OmpF Porin [J] . Valérie Duval, Kimberly Foster, Jennifer Brewster, Frontiers in Microbiology . 2017,第6期

机译：涉及BluR，YcgZ和Lon的新型调控级联控制大肠杆菌 OmpF孔蛋白的表达。
3. Lactoferrin binds to porins OmpF and OmpC in Escherichia coli. [J] . J Erdei, A Forsgren, A S Naidu Infection and immunity . 1994,第4期

机译：乳铁蛋白与大肠杆菌中的孔蛋白OmpF和OmpC结合。
4. DIETARY FUMONISIN Bl EXPOSURE INCREASES PIG SUSCEPTIBILITY TO OPPORTUNISTIC ESCHERICHIA COLI INFECTION AND DECREASES LOCAL INFLAMMATORY CVTOKINE PRODUCTION [C] . I.P. Oswald, S. Fournout, J. Laffitte, Congress of the International Pig Veterinary Society . 2000

机译：膳食Fumonisin BL暴露会增加猪易感性对机会主义大肠杆菌感染，并降低局部炎症性CVTOKINE生产
5. Survival and inactivation of Listeria monocytogenes, shiga toxin-producing Escherichia coli, and multidrug-resistant and susceptible Salmonella serovars exposed to heat and antimicrobials on food contact and food surfaces. [D] . Fouladkhah, Aliyar. 2013

机译：李斯特菌，产志贺毒素的大肠埃希菌以及在食物接触和食物表面暴露于热和抗菌剂的多药耐药和敏感沙门氏菌的存活和失活。
6. Combined Inactivation of lon and ycgE Decreases Multidrug Susceptibility by Reducing the Amount of OmpF Porin in Escherichia coli [O] . Valérie Duval, Hervé Nicoloff, Stuart B. Levy 2009

机译：lon和ycgE联合灭活可通过减少大肠杆菌中OmpF孔蛋白的量来降低多药敏感性。
7. Combined Inactivation of lon and ycgE Decreases Multidrug Susceptibility by Reducing the Amount of OmpF Porin in Escherichia coli▿ [O] . Duval, Valérie, Nicoloff, Hervé, Levy, Stuart B. 2009

机译：lon和ycgE的联合灭活通过减少大肠杆菌中OmpF孔蛋白的量来降低多药敏感性

Combined inactivation of lon and ycgE decreases multidrug susceptibility by reducing the amount of OmpF porin in Escherichia coli.

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