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A case series of intravenous leiomyomatosis and literature review

机译:静脉注射leiomyomatosis和系列文献综述

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Intravenous leiomyomatosis (IVL) is an uncommon benign smooth-muscle tumour of the uterus which invades into uterine and systemic veins. Although benign, this tumour may grow in the absence of, or beyond the confines of a uterine leiomyoma or fibroid, and has the potential to behave aggressively via extension of growth in the venous vasculature, upwards into the inferior vena cava (IVC) and into the right cardiac chambers. This can lead to serious cardiac and pulmonary sequelae. Rarer neurological sequelae and fatal cases have also been reported. Unless there is obvious IVC or intracardiac spread on preoperative imaging, IVL poses a diagnostic challenge. IVL has been reported in the literature as a rare event and is postulated to be more common than previously reported. Potentially this change is related to increased histopathological diagnosis following hysterectomy or fibroid excision. The prognosis of the cases is unknown but requires follow up as recurrence is possible. This paper presents a case series of 12 patients who were diagnosed on post-operative histopathology with IVL in a 20-month period at The Royal Women's Hospital, Victoria, Australia and a literature review of the current management of this unusual disease.
机译:静脉注射leiomyomatosis (IVL)是一种少见良性的子宫平滑肌肿瘤侵入到子宫静脉和系统性。良性的,这种肿瘤生长在缺席的情况下,或子宫平滑肌瘤或的范围之外子宫肌瘤和有潜力的行为积极通过扩展的增长静脉血管,向上到低下腔静脉(IVC)和正确的心脏钱伯斯。肺后遗症。和死亡病例也被报道。有明显的印度河流域文明或心脏内的传播术前成像,IVL构成的诊断挑战。文学作为一种罕见的事件,并假定比先前报道的更普遍。这种变化可能与增加组织病理学诊断后子宫切除术或子宫肌瘤切除。情况下是未知的,但需要跟进的复发是可能的。12系列病例的确诊病人与IVL术后组织病理学20个月期间在皇家女子医院,维多利亚,澳大利亚和文献综述当前这种不寻常的疾病管理。

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