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Diagnosis and management of carotid atherosclerosis

机译:颈动脉的诊断和管理动脉粥样硬化

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Carotid atherosclerosis is a pathological thickening of the common or internal carotid intima, typically into focal areas known as plaques (or atheromata). Although atheromata can remain stable for many years, surface rupture of unstable (vulnerable) plaques leads to local thrombus formation, with subsequent embolisation to the ipsilateral ophthalmic, middle cerebral, or anterior cerebral artery territories. The resultant symptoms are ipsilateral amaurosis fugax or retinal infarction and contralateral body transient ischaemic attack (TIA) or stroke. This review discusses the risk factors, clinical presentation, investigations, and treatment options for symptomatic and asymptomatic carotid atherosclerosis. All references to stenosis use consensus North American Symptomatic Carotid Endarterectomy Trial (NASCET) measurements.1 All recommendations reflect current UK guidelines, unless stated otherwise.
机译:颈动脉粥样硬化是一种病态常见的增厚或颈内动脉内膜,通常被称为焦点地区斑块(或atheromata)。多年保持稳定,表面破裂不稳定斑块导致当地(脆弱)血栓形成,随后embolisation身体的同侧的眼科,大脑中,或大脑前动脉的领土。结果症状侧黑内障fugax或视网膜梗死和侧身体短暂性缺血性发作或中风(TIA)。本文讨论了风险因素,临床报告、调查和处理选项有症状和无症状的颈动脉动脉粥样硬化。共识北美症状性颈动脉动脉内膜切除术(NASCET) measurements.1审判建议反映目前英国的指导方针,除非另有规定。

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