Prevalence of Human Papillomavirus Infection in a Kashmiri Ethnic Female Population

Asia Asiaf; Shiekh Tanveer Ahmad; Muhammad Afzal ZargarShahida Masarat MuftiSyed Hussain Mir

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Prevalence of Human Papillomavirus Infection in a Kashmiri Ethnic Female Population

机译：人类乳头瘤病毒感染的患病率克什米尔民族女性

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Human papillomavirus (HPV) infection is estimated to be the most common sexually transmitted infection and is one of the causal factors in cervical cancer. Understanding the epidemiology of this infection is an important step toward developing strategies for its prevention. Cervical samples from 210 healthy women with normal and abnormal cytomorphology were studied for the detection of HPV DNA by polymerase chain reaction (PCR), utilizing the two most commonly used consensus primer sets. The primers; MY09/MY11 and GP5+/GP6 + located within the L1 region of HPV genome, amplified a broad spectrum of HPV genotypes in a single reaction. The PCR amplification of HPV genomes is a sensitive method that is used for the detection of cervicovaginal HPV. With the aim of identifying the HPV types, samples were also subjected to PCR using specific primers for HPV types 16 and 18. In addition, basic demographic information, sociodemographic characteristics, and sexual behavior were recorded. HPV was detected in 13.8% of the study population aged 18 to 57 years using PCR. HPV16 (6.6%) was more commonly detected than HPV18 (3.8%). The highest prevalence of HPV infection was seen in women below 27 years old, and then, a new increase was seen higher than the age of 48. In conclusion, our study demonstrated that younger age at marriage, economic status, parity, and dwelling are the major risk factors determining HPV infection.

机译：人类乳头瘤病毒(HPV)感染估计是最常见的性传播感染和因果因素之一子宫颈癌。这种感染是一个重要的一步发展战略为其预防。颈样本210名健康女性正常和异常细胞形态学进行了研究通过聚合酶链HPV DNA的检测反应(PCR),利用这两个最常见的使用底漆集共识。MY09 / MY11和GP5 + / GP6 +位于L1地区的人乳头状瘤病毒基因组,放大广泛HPV基因型在一个反应。放大的HPV基因组是一个敏感的方法用于检测cervicovaginal人乳头状瘤病毒。人乳头状瘤病毒类型,样品也受到PCR使用特定的引物对人乳头状瘤病毒类型16和18。此外,基本的人口统计信息,社会人口特征和性行为记录。研究人口的年龄在18岁到57年使用PCR。HPV18(3.8%)。感染被认为27岁以下的女性,然后,一个新的增加被认为高于48岁。年轻的婚姻、经济地位、平价,住宅的主要危险因素确定HPV感染。

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来源
《Genetic testing and molecular biomarkers》 |2012年第8期|904-909|共6页
作者
Asia Asiaf; Shiekh Tanveer Ahmad; Muhammad Afzal ZargarShahida Masarat MuftiSyed Hussain Mir;
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作者单位

Department of Biochemistry, Faculty of Biological Science, University of Kashmir, Srinagar, Jammu and Kashmir, India.;

Department of Medical Elementology and Toxicology, Iamia Hamdard (Hamdard University), Hamdard Nagar, New Delhi, India.;

Department of Obstetrics and Gynecology, Government Medical College, Srinagar, Jammu and Kashmir, India.;

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原文格式 PDF
正文语种英语
中图分类 Q-028;
关键词
Sexually Transmitted Diseases; Marriage Age; InfectionHuman Papillomavirus Infection;

机译：性传播疾病;婚姻年龄;InfectionHuman乳头瘤病毒感染;

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Prevalence of Human Papillomavirus Infection in a Kashmiri Ethnic Female Population

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