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Attitudes and Anticipated Reactions to Genetic Testing for Cancer Among Patients in Mexico City

机译：态度和预期的反应基因测试对癌症患者在墨西哥城

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摘要

The aim of this study was to investigate the attitudes toward cancer predictive genetic testing in a group of non-high-risk women and men and to analyze the factors that may influence their intention to use these tests. We studied a sample of 859 outpatient women and men attending the four tertiary care hospitals of the ISSSTE (Institute of Social Security and Services for Government Employees) in Mexico City. Subjects between the ages of 30 and 74 years with no present or past history of cancer were asked to answer a questionnaire through face-to-face interview. Two different questionnaires were designed, one for women and the other for men, regarding genetic testing of a high-risk gene for breast and prostate cancer, respectively. Descriptive statistics and univariate comparisons were carried out using chi-square test, Wilcoxon's signed rank test, and Friedman test. Multivariate analysis was performed using logistic regression technique. Results showed that the majority of women attended clinics for regular check-ups and for performing screening tests to detect breast cancer, and men did not follow this pattern regarding prostate cancer. Women were more motivated to get genetic testing, more aware about its benefits, and more concerned about having cancer than men.
机译：本研究的目的是调查态度癌症基因预测测试在一群non-high-risk男性和女性并分析可能影响的因素他们打算使用这些测试。样品859门诊男性和女性参加的四个三级保健医院ISSSTE(学院社会保障和服务政府雇员)在墨西哥城。年龄在30和74年的没有现在或过去历史的癌症被要求通过面对面的回答一份调查问卷面试。设计,一个女人和另一个男人,关于基因检测的高危基因乳腺癌和前列腺癌。描述性统计、单变量的比较进行了使用卡方检验,弗里德曼Wilcoxon签署等级测试,测试。多变量分析进行使用逻辑回归技术。大多数的妇女参加了诊所常规体检并进行筛选测试来检测乳腺癌,男人没有关于前列腺癌遵循这种模式。女性更有动力基因检测,更多的意识到它的好处,和担心有比男性癌症。

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