...
  • 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Acta crystallographica. Section D, Structural biology. >Visualizing membrane trafficking through theelectron microscope: cryo-tomography of coatcomplexes
【24h】

Visualizing membrane trafficking through theelectron microscope: cryo-tomography of coatcomplexes

机译：通过可视化膜贩运theelectron显微镜:cryo-tomography的coatcomplexes

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Coat proteins mediate vesicular transport between intracellular compartments,which is essential for the distribution of molecules within the eukaryotic cell.The global arrangement of coat proteins on the membrane is key to theirfunction, and cryo-electron tomography and subtomogram averaging have beenused to study membrane-bound coat proteins, providing crucial structuralinsight. This review outlines a workflow for the structural elucidation of coatproteins, incorporating recent developments in the collection and processing ofcryo-electron tomography data. Recent work on coat protein I, coat protein IIand retromer performed on in vitro reconstitutions or in situ is summarized.These studies have answered long-standing questions regarding the mechanismsof membrane binding, polymerization and assembly regulation of coat proteins.
机译：外套调解之间的膜泡运输的蛋白质细胞内的隔间,是至关重要的分子内的分布真核细胞。theirfunction膜蛋白是关键,和低温电子断层扫描和subtomogram平均有研究膜结合使用外套的蛋白质,提供至关重要的structuralinsight。工作流的结构说明coatproteins,结合最近发展在收集和处理ofcryo-electron断层扫描数据。外壳蛋白IIand retromer进行体外调整或原位了。研究回答了长期存在的问题关于mechanismsof膜绑定,聚合和组装的监管外套蛋白质。

著录项

相似文献

  • 外文文献
  • 中文文献
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号