The silent enemy: Celiac disease goes viral

Reale Alberto; Trevisan Marta; Alvisi GualtieroPalù Giorgio

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The silent enemy: Celiac disease goes viral

机译：沉默的敌人:腹腔疾病病毒

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Celiac disease is a multifactorial autoimmune chronic inflammatory disorder affecting approximately one percent of the worldwide population. In such patients, ingestion of gluten proteins from cereals like wheat, barley, and rye causes damage of the small intestine mucosa, with potentially severe consequences. Onset of the disease in predisposed individuals is believed to require a still not clearly identified external trigger, such as viral infections. A very recent study has begun to shed light on a possible mechanistic basis for this hypothesis, and surprisingly linked intestinal infections caused by common reoviruses to the onset of celiac disease.

机译：乳糜泻是一种多因子的自身免疫性慢性炎性疾病影响全球大约百分之一的人口。蛋白质从谷物小麦,大麦和黑麦小肠黏膜造成损害,潜在的严重后果。疾病倾向的个体被认为要求还不明确确定的外部触发,如病毒感染。研究已经开始阐明一个可能这一假说,机械基础,令人惊讶的是引起肠道感染有关常见的呼吸道出现腹腔疾病。

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来源
《Journal of Cellular Physiology》 |2018年第4期|2693-2694|共2页
作者
Reale Alberto; Trevisan Marta; Alvisi GualtieroPalù Giorgio;
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作者单位

Department of Molecular MedicineUniversity of PaduaPadua,Italy;

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正文语种英语
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关键词
reovirus; Small Intestinal Mucosa; intestinal infectionsUSB OTGCeliac DiseaseGlutensAutoimmunityexternal trigger;

机译：呼肠孤病毒;小肠粘膜肠infectionsUSB OTGCeliac;

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The silent enemy: Celiac disease goes viral

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