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首页> 外文期刊>Archives of Andrology: An International Journal >Oligoasthenozoospermia is not associated with spontaneous abortions following in vivo pregnancies contrasting with in vitro fertilization data.
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Oligoasthenozoospermia is not associated with spontaneous abortions following in vivo pregnancies contrasting with in vitro fertilization data.

机译：与体外受精数据相比，体内妊娠少寡精子症与自然流产无关。

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摘要

Previous data showed an association between low motile density (< 10 million motile/mL) and spontaneous abortion (SAB) following in vitro fertilization-embryo transfer (IVF-ET). The purpose of this study was to determine if the same association existed following intrauterine insemination (IUI). A retrospective review of IUI pregnancies was conducted. Patients with antisperm antibodies, a low hypo-osmotic swelling (HOS) test score (< 50%), or those using donor sperm were excluded. A total of 52 couples were enrolled in the study: 34 in the normal motile density (MD) group and 18 in the low MD group. The SAB rate in the normal group was 29.4% and in the low group was 27.8%. Thus, these data fail to corroborate the conclusions reached after evaluation of IVF pregnancies that low MD is a cause of SAB. However, since there is a large difference in the number of sperm that come in contact with the oocyte following IVF versus IUI, it may be that the implantation defect is not evident until the oocyte is exposed to a certain number of abnormal sperm.
机译：先前的数据显示，在体外受精-胚胎移植（IVF-ET）后，低运动密度（<1000万运动/ mL）与自然流产（SAB）之间存在关联。这项研究的目的是确定子宫内授精（IUI）后是否存在相同的关联。回顾性分析IUI怀孕。排除抗精子抗体，低渗肿胀（HOS）测试分数低（<50％）或使用供体精子的患者。共有52对夫妇参加了研究：正常运动密度（MD）组中的34对夫妇和低MD组中的18对。正常组的SAB率为29.4％，低组为27.8％。因此，这些数据无法证实对IVF妊娠进行评估后得出的结论，即低MD是SAB的原因。然而，由于IVF后与IUI后与卵母细胞接触的精子数量差异很大，可能直到卵母细胞暴露于一定数量的异常精子后，移植缺陷才变得明显。

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