首页> 外文期刊>Archives of gynecology and obstetrics. >The demographic and behavioural profile of women with cervicitis infected with Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum and the comparison of two medical regimens.
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The demographic and behavioural profile of women with cervicitis infected with Chlamydia trachomatis, Mycoplasma hominis and Ureaplasma urealyticum and the comparison of two medical regimens.

机译:感染了沙眼衣原体,人型支原体和解脲支原体的宫颈炎妇女的人口统计学和行为特征,以及两种治疗方案的比较。

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OBJECTIVE: The aim of this study was to compare the therapeutic effect of single dose oral azithromycin with twice-daily, 7-day doxycycline in women with chlamydial, mycoplasmic or ureaplasmic cervicitis and to demonstrate the demographic and behavioral profile of infected women. MATERIALS AND METHODS: Five hundred and thirty-three women with various gynecologic complaints were recruited for this study. All women were screened for Chlamydia trachomatis (CT), Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) by enzyme immune assay tests. Patients positive for Neisseria gonorrhoeae were excluded. Women treated for these infections were tested after completing medical therapy. Educational levels of infected women were similar in each group. The prevalence of CT, UU and MH was 3.4% (18/533), 11.8% (63/533) and 0.9% (5/533), respectively. In 452 patients, no treatment was administered. The remaining patients were either treated with azithromycin (n=41) or doxycycline (n=40). The eradication rate for the infectious agents was 87.3% and 93.5% in the group of azithromycin and doxycycline, respectively (P>0.05). There was no statistically significant difference in efficacy between single dose azithromycin and a 7-day course of doxycycline with respect to the treatment of culture-positive cases. Recurrences were observed in five cases in azithromycin group (12.5%) and in three cases in doxycycline group (7.5%). CONCLUSIONS: The treatment of uncomplicated chlamydial, mycoplasmic and ureaplasmic cervicitis with a single dose of azithromycin administered under supervision in the clinic is as effective as a 7-day course of doxycycline. This regimen may overcome the problem of compliance with the standard twice-daily, 7-day regimen of doxycycline.
机译:目的:本研究的目的是比较单剂量口服阿奇霉素和每日两次,7天强力霉素对衣原体,支原体或脲原体性宫颈炎妇女的治疗效果,并证明受感染妇女的人口统计学和行为特征。材料与方法:本研究共招募了533名患有各种妇科疾病的妇女。通过酶免疫试验对所有妇女进行了沙眼衣原体(CT),解脲脲原体(UU)和人支原体(MH)的筛查。淋病奈瑟氏球菌阳性的患者被排除在外。在接受药物治疗后,对接受过这些感染治疗的妇女进行了测试。每组中受感染妇女的教育水平相似。 CT,UU和MH的患病率分别为3.4%(18/533),11.8%(63/533)和0.9%(5/533)。在452例患者中,未进行任何治疗。其余患者接受阿奇霉素(n = 41)或强力霉素(n = 40)治疗。阿奇霉素和强力霉素组的传染病根除率分别为87.3%和93.5%(P> 0.05)。就培养阳性病例而言,单剂量阿奇霉素和强力霉素7天疗程的疗效无统计学差异。阿奇霉素组有5例复发(12.5%),强力霉素组有3例复发(7.5%)。结论:在临床监督下,单剂量阿奇霉素治疗单纯性衣原体,支原体和脲原体性宫颈炎的效果与强力霉素7天疗程一样有效。该方案可以克服遵守强力霉素每天两次,7天的标准方案的问题。

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