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首页> 外文期刊>Archives of disease in childhood >Pitfalls in the diagnosis of idiopathic pulmonary haemosiderosis.
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Pitfalls in the diagnosis of idiopathic pulmonary haemosiderosis.

机译:诊断特发性肺含铁血黄素沉着症的陷阱。

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摘要

Idiopathic pulmonary haemosiderosis is a very rare but devastating disorder. Diagnosis is sometimes difficult and the clinical course exceedingly variable, as illustrated by this report of a girl, aged 2 years 4 months, with severe iron deficiency anaemia. There was no response to iron therapy and transfusions. Sustained and striking reticulocytosis associated with low haptoglobin mimicked haemolytic anaemia. Positive faecal blood test was documented after repeated testing. There were no pulmonary symptoms. A chest radiograph showed bilateral diffuse alveolar infiltrates. Bronchoalveolar lavage fluid showed numerous siderophages. High resolution computed tomography of the thorax revealed early pulmonary fibrotic changes. Recurrent reticulocytosis appeared to be a very useful sign of recurrent bleeding episodes.
机译:特发性肺含铁血黄素沉着病是一种非常罕见但具有毁灭性的疾病。如本报告所述,一名2岁4个月的女孩患有严重的缺铁性贫血,诊断有时很困难,并且临床过程变化很大。对铁疗法和输血没有反应。与低触珠蛋白类似的持续网状细胞增多与溶血性贫血类似。重复测试后,粪便血液测试呈阳性记录。没有肺部症状。胸部X光片显示双侧弥漫性肺泡浸润。支气管肺泡灌洗液显示出许多噬菌体。胸部的高分辨率计算机断层扫描显示早期肺纤维化改变。复发性网状红细胞增多症似乎是复发性出血发作的非常有用的迹象。

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