Longitudinal Analysis of the Interaction Between Obesity and Pregnancy on Iron Homeostasis: Role of Hepcidin

Eugenia Flores-Quijano Maria; Montalvo-Velarde Irene; Saul Vital-Reyes Victor; Rodriguez-Cruz Maricela; Enrique Rendon-Macias Mario; Lopez-Alarcon Mardia

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Longitudinal Analysis of the Interaction Between Obesity and Pregnancy on Iron Homeostasis: Role of Hepcidin

机译：肥胖和妊娠对铁稳态的相互作用的纵向分析：铁调素的作用

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Background and Aims. When pregnancy occurs in obese women, two opposite mechanisms for iron homeostasis concur: increased need for available iron to support erythropoiesis and decreased iron mobilization from diets and stores due to obesity-related inflammation linked to overexpressed hepcidin. Few studies have examined the role of hepcidin on maternal iron homeostasis in the context of obese pregnancy. The aim of the study was to evaluate the combined effect of maternal obesity and pregnancy on hepcidin and maternal iron status while accounting for inflammation and iron supplementation.

机译：背景和目标。当肥胖妇女怀孕时，铁稳态的两个相反机制是一致的：由于与肥胖有关的铁调素相关的与肥胖有关的炎症，增加了对可用铁的支持以支持红血球生成，以及饮食和储藏中铁的动员减少。很少有研究研究过铁调素在肥胖妊娠背景下对母体铁稳态的作用。该研究的目的是评估孕产妇肥胖和妊娠对铁调素和母亲铁状态的综合影响，同时考虑炎症和铁的补充。

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来源
《Archives of medical research》 |2016年第7期|共7页
作者
Eugenia Flores-Quijano Maria; Montalvo-Velarde Irene; Saul Vital-Reyes Victor; Rodriguez-Cruz Maricela; Enrique Rendon-Macias Mario; Lopez-Alarcon Mardia;
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正文语种 eng
中图分类医药、卫生;
关键词
Iron; Iron deficiency; Pregnancy; Obesity; Hepcidin;

机译：铁;铁缺乏;怀孕;肥胖症;铁调素;

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1. Longitudinal Analysis of the Interaction Between Obesity and Pregnancy on Iron Homeostasis: Role of Hepcidin [J] . Eugenia Flores-Quijano Maria, Montalvo-Velarde Irene, Saul Vital-Reyes Victor, Archives of medical research . 2016,第7期

机译：肥胖和妊娠对铁稳态的相互作用的纵向分析：铁调素的作用
2. Serum Hepcidin Concentrations Decline during Pregnancy and May Identify Iron Deficiency: Analysis of a Longitudinal Pregnancy Cohort in The Gambia [J] . Amat Bah, Sant-Rayn Pasricha, Momodou W Jallow, The Journal of Nutrition: Official Organ of the American Institute of Nutrition . 2017,第6期

机译：妊娠期间血清铁调素浓度下降并可能确定铁缺乏：冈比亚纵向妊娠队列的分析
3. MATERNAL HEPCIDIN DETERMINES FETAL IRON HOMEOSTASIS DURING PREGNANCY [J] . Sangkhae V., Fisher A. L., Chua K., American Journal of Hematology . 2017,第8期

机译：母亲肝素在怀孕期间决定胎儿铁袜
4. Regulation of Body Weight Homeostasis During Pregnancy and Lactation [C] . M. C. Garcia, R. M. Senaris, J. E. Caminos, Conference on Brain Somatic Cross Talk and the Central Control of Metabolism . 2003

机译：怀孕和哺乳期间体重稳态调节
5. Transcriptional regulation of hepcidin, a hormone that maintains iron homeostasis [D] . Wrighting, Diedra M. 2007

机译：铁调素的转录调控，铁调素可维持铁稳态
6. Serum Hepcidin Concentrations Decline during Pregnancy and May Identify Iron Deficiency: Analysis of a Longitudinal Pregnancy Cohort in The Gambia [O] . Amat Bah, Sant-Rayn Pasricha, Momodou W Jallow, -1

机译：妊娠期间血清铁调素浓度下降并可能确定铁缺乏：冈比亚纵向妊娠队列的分析
7. Serum Hepcidin concentrations decline during pregnancy and may identify iron deficiency: Analysis of a longitudinal pregnancy cohort in The Gambia. [O] . Bah, A, Pasricha, S-R, Jallow, MW, 2017

机译：妊娠期间血清Hepcidin浓度下降，并可能发现铁缺乏症：冈比亚纵向妊娠队列的分析。

Longitudinal Analysis of the Interaction Between Obesity and Pregnancy on Iron Homeostasis: Role of Hepcidin

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