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首页> 外文期刊>Archives of disease in childhood >Amitraz poisoning, an emerging problem: epidemiology, clinical features, management, and preventive strategies.
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Amitraz poisoning, an emerging problem: epidemiology, clinical features, management, and preventive strategies.

机译：Amitraz中毒是一个新出现的问题：流行病学，临床特征，管理和预防策略。

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BACKGROUND: Amitraz is a pharmaceutical, veterinary, and agricultural product which is used worldwide under numerous generic names as an acaricide and insecticide. Because of its widespread use amitraz poisoning has come emerged as a cause of childhood poisoning during the past decade, particularly more in certain countries such as Turkey. AIMS AND METHODS: To report the clinical features, the management, and the preventive strategies of amitraz poisoning in nine children, and review the previously reported 137 cases in humans. RESULTS: Five male and four female children aged 10 months to 8 years were admitted to our department. The estimated ingested dose ranged between 89.2 and 163 mg/kg and estimated time from ingestion to presentation was 30-120 minutes. The initial signs and symptoms were impaired consciousness, drowsiness, vomiting, disorientation, miosis, mydriasis, hypotension, bradycardia, tachypnoea, hypothermia, and generalised seizures. Hyperglycaemia, glycosuria, and minimal increase in transaminase levels were observed. None required mechanical ventilation. CNS depression resolved spontaneously within 4-28 hours in all. The length of hospital stay was two to three days; all had a good outcome. CONCLUSION: This review details preventive measures and management strategies of amitraz poisoning, including the importance of following patients closely in the intensive care unit, monitoring their respiratory, cardiovascular, and central nervous systems since they may occasionally experience serious cardiopulmonary side effects.
机译：背景：Amitraz是一种药物，兽医和农产品，在世界范围内以许多通用名称用作杀螨剂和杀虫剂。由于广泛使用，在过去的十年中，尤其是在某些国家（例如土耳其），出现了引起儿童中毒的原因，而导致了中毒。目的和方法：报道9例儿童中双甲酰胺中毒的临床特征，治疗和预防策略，并回顾先前报道的137例人类病例。结果：年龄为10个月至8岁的5名男童和4名女童进入了我科。估计摄入剂量为89.2至163 mg / kg，从摄入到出现的估计时间为30-120分钟。最初的体征和症状为意识障碍，嗜睡，呕吐，迷失方向，瞳孔缩小，瞳孔散大，低血压，心动过缓，心动过速，体温过低和全身性癫痫发作。观察到高血糖，糖尿和转氨酶水平的最小增加。不需要机械通风。总的来说，中枢神经系统抑郁症在4-28小时内自发消失。住院时间为两到三天。所有人都取得了不错的结果。结论：这篇综述详细介绍了双甲酰胺中毒的预防措施和管理策略，包括密切关注重症监护病房，监测其呼吸系统，心血管系统和中枢神经系统的重要性，因为他们有时可能会遇到严重的心肺副作用。

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