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首页> 外文期刊>Archives of dermatological research. >Cosmetic formulations containing Lithospermum erythrorhizon root extract show moisturizing effects on human skin.
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Cosmetic formulations containing Lithospermum erythrorhizon root extract show moisturizing effects on human skin.

机译:含有紫草紫根提取物的化妆品制剂对人体皮肤具有保湿作用。

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摘要

Retention of water in the stratum corneum of skin epidermis plays an important role in regulation of skin function. Loss of water may decline skin appearance gradually and lead to irregular skin disorders. The root extract of Lithospermum erythrorhizon (LES) is known for its various pharmacological activities. However, the potential skin care effect of LES is not clear. The aim of this study was to evaluate the moisturizing efficacy and skin barrier repairing activity of LES. For this study, 30 healthy Asian females (age 20-30) with healthy skin had applied the test emulsions twice daily over a period of 28 days. The skin properties were measured by skin bioengineering techniques. Our preliminary results indicated that LES show moisturizing effect on skin hydration in a time- and dose-dependent pattern, and the maximum increase in skin humidity was 11.77 +/- 1.18% for emulsion LES5.00. Particularly, LES-containing emulsions significantly improve skin barrier function by decreasing the value of transepidermal water loss (TEWL) in a time- and dose-dependent pattern, and the maximum decrease in TEWL value was 7.68 +/- 0.79% for emulsion LES5.00. Taken together, our data demonstrate that LES is more effective in increasing skin humidity and decreasing the TEWL values, indicating the potential skin care effects of LES.
机译:皮肤表皮角质层中水的保留在调节皮肤功能中起重要作用。失水可能会逐渐使皮肤外观下降,并导致不规则的皮肤疾病。紫草紫薇(LES)的根提取物因其多种药理活性而闻名。但是,LES的潜在皮肤护理作用尚不清楚。这项研究的目的是评估LES的保湿功效和皮肤屏障修复活性。在这项研究中,有30名健康的亚洲女性(年龄20-30岁)皮肤健康,在28天的时间内每天两次使用测试乳液。皮肤特性通过皮肤生物工程技术测量。我们的初步结果表明,LES对皮肤水分的保湿作用呈时间和剂量依赖性,乳液LES5.00的皮肤湿度最大增加为11.77 +/- 1.18%。尤其是,含LES乳液通过以时间和剂量依赖性方式降低表皮失水(TEWL)的值来显着改善皮肤屏障功能,乳液LES5的TEWL值的最大降低为7.68 +/- 0.79%。 00综上所述,我们的数据表明,LES在增加皮肤湿度和降低TEWL值方面更有效,表明LES有潜在的皮肤护理作用。

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