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Resuscitated babies are more likely to have low intelligence at 8 years Neonates who needed resuscitation at birth were more likely than normal neonates to have a low IQ at the age of 8 in a cohort study from the UK. As expected, the risk was highest for neonates with signs of encephalopathy (23.1% v 6.5%; adjusted odds ratio 6.22, 95% CI 1.57 to 24.65). The new finding was that of a link between an IQ of less than 80 and resuscitation in neonates without signs of cerebral injury (9.8% v 6.5%; 1.65,1.13 to 2.43).The authors analysed data from a long standing cohort of more than 11000 children born in 1991 and 1992. They adjusted for most con-founders and defined resuscitation at birth as the need for chest compressions or assisted respiration via a mask or an endotracheal tube.Only 5953 children completed the Weseh-ler intelligence scale at 8 years, but sensitivity analyses accounting for the missing data made little difference to the results. The smaller numbers may have decreased the study's power, however. The overall IQ of children who were resuscitated at birth without encephalopathy was lower, but not significantly lower than the IQ of normal controls (mean difference, -0.99, -2.58 to 0.60). One further caveat is that the authors had no data on maternal smoking or alcohol consumption, both of which might have an effect on resuscitation requirements, and on later intelligence.
机译:复苏的婴儿更有可能低在8年新生儿智力复苏在出生时更有可能比正常新生儿有一个低智商8岁来自英国的队列研究。新生儿的风险最高的迹象脑病(23.1% v 6.5%;6.22, 95%可信区间1.57到24.65)。的智商低于80和之间的联系在新生儿复苏的迹象脑损伤(9.8% v 6.5%;2.43)。站群出生的11000多名儿童在1991年和1992年。con-founders和出生时定义的复苏胸外按压或辅助的必要性通过面具或气管内呼吸管。智力量表在8年,但灵敏度分析会计缺失的数据对结果的影响微乎其微。数字可能会降低研究的力量,然而。复苏在出生时没有脑病低,但不是明显低于的智商正常对照组(平均差,-0.99,-2.580.60)。没有数据在母亲吸烟或饮酒消费,两者都可能有影响复苏的需求,和以后情报。

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