首页> 外文期刊>Archives of disease in childhood. Fetal and neonatal edition >Demographics, clinical characteristics and outcomes of neonates diagnosed with fetomaternal haemorrhage.
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Demographics, clinical characteristics and outcomes of neonates diagnosed with fetomaternal haemorrhage.

机译:被诊断患有胎儿母体出血的新生儿的人口统计学,临床特征和结局。

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To determine clinical characteristics, demographics and short-term outcomes of neonates diagnosed with fetomaternal haemorrhage (FMH).The authors analysed the Nationwide Inpatient Sample, 1993 to 2008. Singleton births diagnosed with FMH were identified by International Classification of Diseases (ICD-9) code 762.3. Descriptive, univariate and multivariable regression analyses were performed to determine the national annual incidence of FMH over time as well as demographics and clinical characteristics of neonates with FMH.FMH was identified in 12 116 singleton births. Newborns with FMH required high intensity of care: 26.3% received mechanical ventilation, 22.4% received blood product transfusion and 27.8% underwent central line placement. Preterm birth (OR 3.7), placental abruption (OR 9.8) and umbilical cord anomaly (OR 11.4) were risk factors for FMH. Higher patient income was associated with increased likelihood of FMH diagnosis (OR 1.2), and Whites were more likely to be diagnosed than ethnic minorities (OR 1.9). There was reduced frequency of diagnosis in the Southern USA (OR 0.8 vs the Northeastern USA).Diagnosis of FMH is associated with significant morbidity as well as regional, socioeconomic and racial disparity. Further study is needed to distinguish between diagnostic coding bias and true epidemiology of the disease. This is the first report of socioeconomic and racial/ethnic disparities in FMH, which may represent disparities in detection that require national attention.
机译:为确定诊断为胎儿母系出血(FMH)的新生儿的临床特征,人口统计学和近期结局。作者分析了1993年至2008年的全国住院患者样本。通过国际疾病分类(ICD-9)确定了诊断为FMH的单胎婴儿。代码762.3。进行描述性,单变量和多变量回归分析,以测定全国FMH随时间推移的年发病率以及FMH新生儿的人口统计学和临床​​特征。在12 116个单胎婴儿中鉴定出FMH。患有FMH的新生儿需要高强度的照护:26.3%的患者接受了机械通气,22.4%的患者接受了血液输血,27.8%的患者接受了中线放置。早产(OR 3.7),胎盘早剥(OR 9.8)和脐带异常(OR 11.4)是FMH的危险因素。较高的患者收入与FMH诊断的可能性增加有关(OR 1.2),与白人相比,白人的诊断可能性更高(OR 1.9)。在美国南部,诊断频率降低(相对于美国东北部,诊断率为0.8)。FMH的诊断与高发病率以及地区,社会经济和种族差异有关。需要进一步研究以区分诊断编码偏倚和疾病的真正流行病学。这是FMH中社会经济和种族/种族差异的第一份报告,这可能代表需要全国关注的侦查差异。

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