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首页> 外文期刊>Applied optics >Optical Doppler velocimetry at various retinal vessel depths by variation of the source coherence length
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Optical Doppler velocimetry at various retinal vessel depths by variation of the source coherence length

机译：通过改变源相干长度，在不同的视网膜血管深度进行光学多普勒测速

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摘要

We report on what we believe is a novel approach to measuring the velocity of red blood cells (RBC's) at different depths of retinal vessels by use of low-coherence sources. The technique, variable coherence optical Doppler velocimetry (VCODV), performs Doppler shift measurements through autodyne mixing between the light scattered by the RBC's and by the vessel front wall (reference). Only the light from RBC's moving at a depth less than half the coherence length (CL) mixes efficiently with the reference. Measurements of the Doppler shifts from RBC's with sources of four different CL's in a 152-μm vein of a volunteer confirmed the feasibility of VCODV. This approach has the potential to monitor in vivo retinal RBC velocity gradient at the vessel wall and the velocity profile within the blood vessel in the condition of symmetric blood flow profiles.
机译：我们报告了我们认为是通过使用低相干性源来测量视网膜血管不同深度处的红细胞（RBC）速度的一种新颖方法。这项技术是可变相干光学多普勒测速仪（VCODV），它通过RBC和血管前壁（参考）散射的光之间的自动达因混合来执行多普勒频移测量。只有来自RBC的光移动的深度小于相干长度（CL）的一半，才能与参考有效混合。在志愿者的152-μm静脉中测量来自RBC和四个不同CL来源的多普勒频移，证实了VCODV的可行性。该方法具有在对称血流轮廓的情况下监测血管壁处的体内视网膜RBC速度梯度和血管内速度轮廓的潜力。

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