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VESICLE SIZING BY STATIC LIGHT SCATTERING - A FOURIER COSINE TRANSFORM APPROACH

机译:静态光散射对船只进行尺寸设定-傅立叶余弦变换方法

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A Fourier cosine transform method, based on the Rayleigh-Gans-Debye thin-shell approximation, was developed to retrieve vesicle size distribution directly from the angular dependence of scattered light intensity. Its feasibility for real vesicles was partially tested on scattering data generated by the exact Mie solutions for isotropic vesicles. The noise tolerance of the method in recovering unimodal and biomodal distributions was studied with the simulated data. Applicability of this approach to vesicles with weak anisotropy was examined using Mie theory for anisotropic hollow spheres. A primitive theory about the first four moments of the radius distribution about the origin, excluding the mean radius, was obtained as an alternative to the direct retrieval of size distributions. [References: 18]
机译:开发了一种基于瑞利-甘斯-德拜(Rayleigh-Gans-Debye)薄壳近似的傅里叶余弦变换方法,可直接从散射光强度的角度依赖性中检索小泡大小分布。对于各向同性囊泡的精确Mie解产生的散射数据,部分测试了其在实际囊泡中的可行性。利用模拟数据研究了该方法在恢复单峰和生物峰分布中的噪声容忍度。使用各向异性空间空心球的米氏理论研究了这种方法对具有弱各向异性的囊泡的适用性。作为直接获取尺寸分布的替代方法,获得了有关原点半径分布的前四个矩(不包括平均半径)的原始理论。 [参考:18]

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