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Theoretical and experimental investigation of near-infrared light propagation in a model of the adult head

机译:成年头部模型中近红外光传播的理论和实验研究

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Near-infrared light propagation in various models of the adult head is analyzed by both time-of-flight measurements and mathematical prediction. The models consist of three- or four-layered slabs, the latter incorporating a clear cerebrospinal fluid (CSF) layer. The most sophisticated model also incorporates slots that imitate sulci on the brain surface. For each model, the experimentally measured mean optical path length as a function of source-detector spacing agrees well with predictions from either a Monte Carlo model or a finite-element method based on diffusion theory or a hybrid radiosity-diffusion theory. Light propagation in the adult head is shown to be highly affected by the presence of the clear CSF layer, and both the optical path length and the spatial sensitivity profile of the models with a CSF layer are quite different from those without the CSF layer. However, the geometry of the sulci and the boundary between the gray and the white matter have little effect on the detected light distribution. (C) 1991 Optical Society of America
机译:通过飞行时间测量和数学预测来分析在成年头的各种模型中近红外光的传播。模型由三层或四层平板组成,后者包含透明的脑脊液(CSF)层。最复杂的模型还包含模仿大脑表面沟渠的槽。对于每个模型,实验测量的平均光程长度作为源探测器间隔的函数,与基于蒙特卡洛模型或基于扩散理论或混合辐射度扩散理论的有限元方法的预测非常吻合。透明CSF层的存在严重影响了成年头中的光传播,具有CSF层的模型的光程长度和空间灵敏度分布与没有CSF层的模型完全不同。但是,沟的几何形状以及灰色和白色物质之间的边界对检测到的光分布影响很小。 (C)1991年美国眼镜学会

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