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首页> 外文期刊>Applied optics >Optimal beam size for light delivery to absorption-enhanced tumors buried in biological tissues and effect of multiple-beam delivery: A Monte Carlo study
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Optimal beam size for light delivery to absorption-enhanced tumors buried in biological tissues and effect of multiple-beam delivery: A Monte Carlo study

机译：最佳光束大小，用于将光传输到生物组织中埋藏的吸收增强型肿瘤中，以及多光束传输的效果：蒙特卡洛研究

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Optimal laser light delivery into turbid biological tissues was studied by using Monte Carlo simulations based on the delta-scattering technique. The goal was to deliver efficiently the maximum amount of optical power into buried tumors being treated while avoiding potential damage to normal tissue caused by strong optical power deposition underneath the tissue surface illuminated by the laser beam. The buried tumors were considered to have much higher absorption than the surrounding normal tissue because of selective uptake of the absorption-enhancement dye. The power delivering efficiency to buried tumors was investigated for various diameters of the laser beam. An optimal beam diameter was estimated to achieve the maximum product of the power coupling efficiency and the power delivered to the buried tumor. The distribution of power deposition was simulated for single-beam delivery and The simulated results showed that with an appropriate dye enhancement and an optimal laser delivery configuration, a high selectivity for laser treatment of tumor could be achieved. (C) 1997 Optical Society of America.
机译：通过基于增量散射技术的蒙特卡罗模拟研究了向浑浊的生物组织中的最佳激光传输。目的是将最大的光功率有效地传递到正在治疗的埋藏肿瘤中，同时避免由于激光束照射的组织表面下方强大的光功率沉积而对正常组织造成潜在的损害。由于选择性吸收吸收增强染料，因此认为埋藏的肿瘤具有比周围正常组织更高的吸收。针对各种直径的激光束，研究了掩埋肿瘤的功率传输效率。估计最佳光束直径以实现功率耦合效率和传递到埋藏肿瘤的功率的最大乘积。模拟了单束传输的功率沉积分布，模拟结果表明，通过适当的染料增强和最佳的激光传输配置，可以实现激光对肿瘤的高选择性。 （C）1997年美国眼镜学会。

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