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首页> 外文期刊>Annals of surgical oncology >Upper extremity reconstruction following resection of soft tissue sarcomas: a functional outcomes analysis.
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Upper extremity reconstruction following resection of soft tissue sarcomas: a functional outcomes analysis.

机译：切除软组织肉瘤后的上肢重建：功能结果分析。

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摘要

BACKGROUND: Treatment for soft tissue sarcoma of the upper extremity has evolved to include limb salvage techniques. We reviewed our experience with limb salvage therapy for upper extremity sarcomas with an emphasis on functional outcomes following the reconstructive surgery. METHODS: A retrospective analysis was performed of 81 consecutive patients with soft tissue sarcoma of the upper extremity who had limb salvage therapy with reconstruction by a plastic surgeon. Univariate and multivariate regression analyses of relevant outcome variables were performed. Enneking functional scores were obtained from 43 patients. RESULTS: The study included 16 microvascular reconstructions and 67 non-microvascular reconstructions for a total of 83 reconstructions in 81 patients. The mean defect size was 129 cm(2) (standard deviation: 106 cm(2)). The mean total functional score was 23.1 (range, 9 to 30). Any reconstruction-related complication and preoperative chemotherapy use were associated with a 7.3 point (P = .03) and 4.7 point (P = .01) decrease in total functional score, respectively. Kaplan-Meier product-limit analysis showed 82% 5-year overall survival and 67% 5-year disease-free survival rates. CONCLUSIONS: For soft tissue sarcoma of the upper extremity, limb salvage with good functional outcome is possible with a judicious approach to reconstruction.
机译：背景：上肢软组织肉瘤的治疗已发展为包括肢体挽救技术。我们回顾了肢体抢救治疗上肢肉瘤的经验，重点是重建手术后的功能结局。方法：回顾性分析81例连续性上肢软组织肉瘤患者，这些患者接受整形外科医生的翻身治疗。对相关结果变量进行了单因素和多因素回归分析。从43例患者中获得功能性评分。结果：该研究包括16例微血管重建和67例非微血管重建，共81例患者进行了83例重建。平均缺陷尺寸为129 cm（2）（标准偏差：106 cm（2））。平均总功能评分为23.1（范围为9到30）。任何与重建相关的并发症和术前使用化疗均会使总功能评分分别降低7.3点（P = .03）和4.7点（P = .01）。 Kaplan-Meier产品极限分析显示82％的5年总生存率和67％的5年无病生存率。结论：对于上肢软组织肉瘤，采用明智的重建方法可以挽救具有良好功能结果的肢体。

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