• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>The journal of applied laboratory medicine. >Myositis Antibodies and Interstitial Lung Disease
【24h】

Myositis Antibodies and Interstitial Lung Disease

机译：肌炎和间质性肺疾病的抗体

获取原文
获取原文并翻译 | 示例
       
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Background: Interstitial lung disease (ILD) comprises a heterogeneous group of inflammatory and fibrotic conditions, often resulting in progressive lung function decline and increased mortality. Connective tissue disease (CTD) should be considered in all patients with ILD, as distinguishing between CTD-ILD and other forms of fibrotic lung disease has important therapeutic and prognostic implications. The idiopathic inflammatory myopathies (IIM) represent a CTD subtype of growing interest to ILD experts. The expansion and availability of myositis-specific and myositis-associated antibody testing has allowed for improved disease detection and characterization. Content: In this review, we highlight the relationship between myositis antibodies and ILD. Select forms of IIM, such as the antisynthetase syndrome and clinically amyopathic dermatomyositis can present with rapidly progressive ILD, warranting timely disease diagnosis and management. Disease phenotypes, prevalence, laboratory testing, prognosis, and management strategies are described according to select myositis antibodies. Summary: Myositis antibodies provide valuable information for clinicians managing patients with ILD. This review aims to increase awareness of their role in disease detection, pathophysiology, and possibly therapeutics.
机译：背景:间质性肺病(ILD)由炎症的异质群体和纤维化的条件,往往导致进步的肺功能下降和增加死亡率。被认为是在所有患者ILD,区分CTD-ILD和其他形式的肺纤维化疾病具有重要的治疗和预后的影响。炎性肌病(IIM)代表CTD亚型ILD越来越感兴趣的专家。myositis-specific扩张和可用性和myositis-associated抗体测试允许检测和改善疾病鉴定。突出肌炎的关系抗体和ILD。antisynthetase综合症,临床诊断amyopathic皮肌炎可以存在快速进行性ILD,需要及时疾病诊断和管理。表型、患病率、实验室测试、预后和管理策略根据描述选择肌炎抗体。对临床医师管理有价值的信息ILD患者。在疾病检测意识的作用,病理生理学,和可能的治疗。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号