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首页> 外文期刊>The journal of applied laboratory medicine. >Preeclampsia: New Decade, New Diagnostic Efforts
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Preeclampsia: New Decade, New Diagnostic Efforts

机译：子痫前期:新十年,新诊断的努力

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Preeclampsia is a pernicious, multisystem disorder in the setting of pregnancy. The definition of preeclampsia, revised in the last decade, is hypertension developing after 20 weeks gestation with one or more of the following clinical symptoms: proteinuria, organ dysfunction, or fetal growth restriction (1, 2). Of note, the current definition does not require proteinuria to meet the diagnostic criteria. Globally, this complex disorder affects -2% of pregnancies and is a significant cause of maternal and perinatal morbidity and mortality (3). Risk factors include a history of preeclampsia or hypertension in a previous pregnancy, chronic kidney disease, diabetes, chronic hypertension, and autoimmune disease (4). In severe cases, preeclampsia leads to eclamptic seizures and life-threatening hemolysis, elevated liver enzymes, and low platelet (HELLP) syndrome. Early preeclampsia (<34weeks gestation) rather than late preeclampsia confers increased perinatal mortality and morbidity risk and both short- and long-term maternal complications.
机译：子痫前期是有害的,多系统疾病在怀孕的设置。子痫前期,在过去的十年中,修正高血压妊娠20周后发展与一个或多个以下临床症状:蛋白尿、器官功能障碍或胎儿生长受限(1、2)。值得注意的是,目前的定义不需要蛋白尿符合诊断标准。复杂的障碍影响-2%的妊娠和孕产妇和围产期的重要原因吗发病率和死亡率(3)风险因素包括子痫前期或高血压的历史以前怀孕,慢性肾脏疾病,糖尿病、慢性高血压,和自身免疫性(4)疾病。在严重的情况下,子痫前期线索惊厥的发作和危及生命溶血、肝酶升高和低血小板综合征(临床上妊娠)。(< 34周妊娠),而不是晚了子痫前期可以提高围产期风险和短期和死亡率和发病率长期孕产妇并发症。

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