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首页> 外文期刊>Journal of vitreoretinal diseases. >Intravitreal Rituximab-Associated Retinal Occlusive Vasculitis
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Intravitreal Rituximab-Associated Retinal Occlusive Vasculitis

机译:玻璃体内注射利妥昔单抗相关性视网膜闭塞性血管炎

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摘要

Purpose: To describe a 90-year-old patient who was referred to a private retina specialist with gradually worsening vision and floaters in the left eye. Methods: A retrospective case report is presented. Results: The patient was treated with intravitreal rituximab injections for intraocular lymphoma with resulting vision loss to the level of hand motions from severe granulomatous uveitis and retinal occlusive vasculitis. Conclusions: Retinal occlusive vasculopathy secondary to rituximab intravitreal injections is a rare clinical entity with only a single previous case reported in the literature. However, there are reports of systemic vasculitis after systemic administration of rituximab. Clinicians should be aware of the possibility of ocular hypertension, granulomatous anterior uveitis, and/or retinal occlusive vasculitis after intravitreal rituximab use. Consideration should be given to the inflammatory risk of rituximab intravitreal injections to reduce the potential for treatment-induced vision loss.
机译:目的:描述一个90岁的病人指私人视网膜专家逐渐恶化愿景和飞蚊症左眼。提出了。intravitreal利妥昔单抗为眼内注射淋巴瘤与水平导致视力丧失严重的肉芽肿性葡萄膜炎的手势和视网膜闭塞性血管炎。视网膜闭塞性血管病变继发于美罗华intravitreal注射是一种罕见的临床实体只有一个先前的案例在文献中报道。系统性血管炎的报告系统政府的利妥昔单抗。注意眼部高血压的可能性,肉芽肿性前葡萄膜炎,视网膜和/或intravitreal利妥昔单抗后闭塞的血管炎使用。炎症美罗华intravitreal的风险减少潜在的注射treatment-induced视力丧失。

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