It is well accepted that reactive oxygen species play a key role in pathogenesis of various diseases, including Alzheimer's, Huntington's, Parkinson's and cancer (Kell 2010). An important underlying mechanism is the continuous, auto-catalytic generation of. hydroxyl radicals by the Fenton reaction, involving poorly liganded iron. It is also well known that a healthy diet may prevent various diseases, including cancer (Amin et al. 2009; Kim et al. 2010; Park 2012; Reif and Bolt 2012). Despite the intensive research, it, however, remains unclear which specific dietary compounds are beneficial (Bjelakovic and Gluud 2007). Nevertheless, it seems plausible that antioxidative components of plants, including flavonoids, beta-carotene and vitamin E, play a major role (Wolfle et al. 2013; Li et al. 2011; Stewart and Marchan 2012; Marchan 2011).
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