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首页> 外文期刊>Arthritis and Rheumatism >Is the 'lipid paradox' in rheumatoid arthritis really a paradox? Comment on the article by Bartels et al.
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Is the 'lipid paradox' in rheumatoid arthritis really a paradox? Comment on the article by Bartels et al.

机译：类风湿关节炎中的“脂质悖论”真的是悖论吗？评论Bartels等人的文章。

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摘要

A recent analysis by Bartels and colleagues (1) among Medicare patients with rheumatoid arthritis (RA) revealed that although these patients are at increased risk of cardiovascular disease (CVD), primary lipid screening was performed in only 45%. Various explanations exist, but an interesting possibility is the complex relationship between lipids and RA, which may perplex physicians and lead them to doubt the significance of lipids in the pathogenesis of CVD in patients with RA. This complexity was highlighted in a Mayo Clinic study by Myasoedova et al (2), in which RA patients with lower total and low-density lipoprotein (LDL) cholesterol levels had a higher CVD risk than those with higher cholesterol levels.
机译：Bartels及其同事（1）最近对类风湿关节炎（RA）的Medicare患者进行的分析显示，尽管这些患者罹患心血管疾病（CVD）的风险增加，但仅进行了45％的初次脂质筛查。存在各种解释，但有趣的可能性是脂质与RA之间的复杂关系，这可能使医师感到困惑，并使他们怀疑脂质在RA患者CVD发病机理中的重要性。 Myasoedova等人（2）的Mayo诊所研究强调了这种复杂性，在该研究中，总胆固醇和低密度脂蛋白（LDL）胆固醇水平较低的RA患者比胆固醇水平较高的RA患者的CVD风险更高。

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