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首页> 外文期刊>Asian Journal of Chemistry: An International Quarterly Research Journal of Chemistry >Difference Speetrophotometric Method for the Determination of Metronidazole in Tablets
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Difference Speetrophotometric Method for the Determination of Metronidazole in Tablets

机译：差示分光光度法测定片剂中甲硝唑的含量

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摘要

In this work,a simple,sensitive and rapid speetrophotometric method is proposed for determination of metronidazole.The method is based on the induced spectral changes upon changing the pH of the medium and measured the difference in absorbance at 326 nm.The difference absorbance(AA)is linear in the concentration over the range 2.0-40.0 mu g/mL(r~2=0.999),with a detection limit 0.76 mu g/mL.The method was successfully applied to the commercial pharmaceutical drug without interference from common ingredients accompanying the drug.The obtained results are in good agreement with those obtained by official methods.
机译：本文提出了一种简单，灵敏，快速的分光光度法测定甲硝唑，该方法基于改变介质pH值引起的光谱变化并测量326 nm处的吸光度差。浓度在2.0-40.0μg / mL（r〜2 = 0.999）范围内呈线性，检出限为0.76μg / mL，该方法成功应用于商业药物，不受常见成分的干扰所获得的结果与通过官方方法获得的结果非常一致。

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