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首页> 外文期刊>Artificial cells, blood substitutes, and biotechnology >Synthesis of microwave-assisted poly(methyl vinyl ether-co-maleic anhydride)-bovine serum albumin bioconjugates.
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Synthesis of microwave-assisted poly(methyl vinyl ether-co-maleic anhydride)-bovine serum albumin bioconjugates.

机译:微波辅助聚(甲基乙烯基醚-马来酸酐共聚物)-牛血清白蛋白生物共轭物的合成。

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摘要

The water-soluble poly(methyl vinyl ether-co-maleic anhydride) copolymer-bovine serum albumin bioconjugates were synthesized in the presence of 1-ethyl-3-(3-dimetilamino-propyl) carbodiimide hydrochloride as cross-linking agents via microwave-assisted and conventional methods and characterized by size-exclusion chromatography and high-performance liquid chromatography. According to size-exclusion chromatography and high-performance liquid chromatography results, the bioconjugates synthesized in the microwave-assisted method are more stable and efficient than the conventional method. The reaction time is shortened from 17 hours to 15 minutes by means of the microwave-assisted method.
机译:水溶性聚(甲基乙烯基醚-马来酸酐)共聚物-牛血清白蛋白生物共轭物是在1-乙基-3-(3-二美氨基-丙基)碳二亚胺盐酸盐作为交联剂的存在下通过微波-微波合成的。辅助和常规方法,其特征在于尺寸排阻色谱法和高效液相色谱法。根据体积排阻色谱法和高效液相色谱法的结果,微波辅助法合成的生物共轭物比常规方法稳定,高效。通过微波辅助方法,反应时间从17小时缩短至15分钟。

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