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Poly(ether imide) Scaffolds as Multifunctional Materials for Potential Applications in Regenerative Medicine.

机译:聚(醚酰亚胺)支架作为多功能材料在再生医学中的潜在应用。

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摘要

This article gives an overview of scaffolds that can be prepared from poly(ether imide) (PEI). These scaffolds were developed for extracorporeal blood detoxification processes in which specific compounds from blood or plasma are removed selectively. Both the preparation of porous microparticles and the preparation of hollow fibers are described. Commercially available particulate support materials have the disadvantage of a low accessibility of the internal pore system, a poor flow-through behavior and low adsorption specificity. Thus, novel support materials with optimally adapted properties profiles are needed. The second part of this article shows some recently developed highly asymmetric PEI hollow fibers. PEI scaffolds can be considered multifunctional because they combine separation characteristics, biocompatibility, sufficient biostability, and the possibility of creating tailor-made biofunctional surfaces.
机译:本文概述了可以由聚醚酰亚胺(PEI)制备的支架。这些支架被开发用于体外血液排毒过程,其中选择性地从血液或血浆中去除特定化合物。描述了多孔微粒的制备和中空纤维的制备。市售的颗粒状载体材料的缺点是内部孔隙系统的可及性低,流通性差和吸附特异性低。因此,需要具有最佳适应特性曲线的新型支撑材料。本文的第二部分显示了一些最近开发的高度不对称的PEI中空纤维。 PEI支架可以被认为是多功能的,因为它们结合了分离特性,生物相容性,足够的生物稳定性以及创建量身定制的生物功能表面的可能性。

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