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A human lymph node in vitro-challenges and progress.

机译:人类淋巴结在体外的挑战和进展。

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摘要

Extracorporeal human lymphatic organs are expected to be excellent tools in the study of human molecular and cellular bases of the immunologic balance and tissue harmony. A rational approach and process to design a device and a procedure to recreate the human lymph node environment in vitro is described with emphasis on T-cell activation. Based on this approach, a bioreactor and a process supporting self-assembly of human lymphatic tissues due to proper emulation of human architecture and homeostasis could be developed.
机译:人体体外淋巴器官有望成为研究人体分子和细胞免疫平衡和组织和谐基础的优秀工具。描述了设计设备和程序以在体外重建人淋巴结环境的合理方法和过程,重点是T细胞活化。基于这种方法,可以开发生物反应器和由于人类结构和体内平衡的正确模拟而支持人类淋巴组织自组装的过程。

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