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Opening-wedge high tibial osteotomy with and without bone graft.

机译:带或不带骨移植的楔形高位胫骨截骨术。

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Medial opening-wedge has gained popularity in comparison to other techniques of high tibial osteotomy. This technique involves the creation of a gap in the tibia. Filling the gap with autologous iliac bone graft was recommended in the classic description, to prevent complications such as correction loss or delayed bone union. No previous reports have compared grafted and nongrafted osteotomies. This study hypothesized that the use of autologous bone graft in medial opening-wedge high tibial osteotomy (MOWHTO) less than 12.5 mm is unnecessary. A prospective randomized clinical trial was conducted. Forty-six opening-wedge high tibial osteotomies were carried out between April 2007 and December 2008. All had fixation with a type of Puddu stainless steel plate and screws. Patients were randomly divided by software analysis into two groups: group A had osteotomies that were filled with autologous bone graft and group B had osteotomies that were unfilled. Autologous iliac bone graft was harvested in both groups. Clinical and radiographic evaluations were performed twice monthly by blinded investigators. The rates of complications were compared between the groups. There was no difference in demographic data. Mean time to clinical bone union in group A was 12.4 weeks (confidence interval [CI] 11.2-13.6) and in group B was 13.7 weeks (CI 12.5-14.9), but this difference was not significant (P = 0.13). Signals of correction loss occurred in one patient (4.35%) in group A, and in two patients (8.70%) in group B. All osteotomies had achieved bone union. It was concluded that time to bone union was not statistically different between the group with bone graft and the group without graft.
机译:与其他胫骨高位截骨术相比,内侧楔形术已广受欢迎。该技术涉及在胫骨中形成缝隙。在经典描述中,建议使用自体bone骨移植物填充间隙,以防止并发症,例如矫正损失或延迟骨结合。以前没有报道比较移植和非移植截骨术。这项研究假设,在小于12.5 mm的内侧开口楔高位胫骨截骨术(MOWHTO)中使用自体骨移植术是不必要的。进行了一项前瞻性随机临床试验。在2007年4月至2008年12月之间进行了46例开放楔高位胫骨截骨术。所有患者均用Puddu不锈钢板和螺钉固定。通过软件分析将患者随机分为两组:A组截骨处充满自体骨移植物,B组截骨处未充满骨。两组均收集自体骨移植物。盲法研究者每月两次进行临床和放射学评估。比较两组之间的并发症发生率。人口统计数据没有差异。 A组的平均临床骨结合时间为12.4周(置信区间[CI] 11.2-13.6),B组为13.7周(CI 12.5-14.9),但差异无统计学意义(P = 0.13)。 A组中一名患者(4.35%)发生矫正损失的信号,B组中两名患者(8.70%)发生矫正损失。所有截骨术均已达到骨结合。结论是,植骨组和未植骨组的骨愈合时间在统计学上没有差异。

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