• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Artificial Organs >Evaluation of inflow cannulation site for implantation of right-sided rotary ventricular assist device
【24h】

Evaluation of inflow cannulation site for implantation of right-sided rotary ventricular assist device

机译：右侧旋转心室辅助装置植入的插管部位评估

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

Right heart dysfunction is one of the most serious complications following implantation of a left ventricular assist device, often leading to the requirement for short- or long-term right ventricular assist device (RVAD) support. The inflow cannulation site induces major hemodynamic changes and so there is a need to optimize the site used depending on the patient's condition. Therefore, this study evaluated and compared the hemodynamic influence of right atrial cannulation (RAC) and right ventricular cannulation (RVC) inflow sites. An in vitro variable heart failure mock circulation loop was used to compare RAC and RVC in mild and severe biventricular heart failure (BHF) conditions. In the severe BHF condition, higher ventricular ejection fraction (RAC: 13.6%, RVC: 32.7%) and thus improved heart chamber and RVAD washout were observed with RVC, which suggested this strategy might be preferable for long-term support (i.e., bridge-to-transplant or destination therapy) to reduce the risk of thrombus formation. In the mild BHF condition, higher pulmonary valve flow (RAC: 3.33L/min, RVC: 1.97L/min) and lower right ventricular stroke work (RAC: 0.10W, RVC: 0.13W) and volumes were recorded with RAC. These results indicate an improved potential for myocardial recovery, thus RAC should be chosen in this condition. This in vitro study suggests that RVAD inflow cannulation site should be chosen on a patient-specific basis with a view to the support strategy to promote myocardial recovery or reduce the risk of long-term complications.
机译：右心功能不全是植入左心室辅助设备后最严重的并发症之一，通常导致需要短期或长期的右心室辅助设备（RVAD）支持。流入的插管部位引起主要的血流动力学变化，因此需要根据患者的状况优化所用部位。因此，本研究评估并比较了右心房插管（RAC）和右心室插管（RVC）流入部位对血液动力学的影响。体外可变心力衰竭模拟循环回路用于比较轻度和重度双室性心力衰竭（BHF）条件下的RAC和RVC。在严重的BHF患者中，RVC观察到较高的心室射血分数（RAC：13.6％，RVC：32.7％），从而改善了心腔和RVAD冲洗，这表明该策略可能更适合长期支持（即桥-移植或目的地疗法）以减少血栓形成的风险。在轻度BHF情况下，用RAC记录了更高的肺动脉瓣流量（RAC：3.33L / min，RVC：1.97L / min）和较低的右心室中风功（RAC：0.10W，RVC：0.13W）。这些结果表明改善了心肌恢复的潜力，因此应在这种情况下选择RAC。这项体外研究表明，应根据患者的具体情况选择RVAD入流插管部位，以寻求支持策略以促进心肌恢复或减少长期并发症的风险。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号