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Estimation of Mechanical Heart Valve Cavitation in an Electro-hydraulic Total Artificial Heart.

机译:电动全人工心脏中机械性心脏瓣膜空化的估计。

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The purpose of this study was to establish a method for estimating mechanical in vitro heart valve cavitation in an electro-hydraulic total artificial heart (EHTAH). The variations in the left driving pressure (LDP) slope of the EHTAH were used as an index of the cavitation intensity. The LDP slope was controlled by changing the stroke volume of the EHTAH. The stroke volume was changed from full-filling and full-eject to partial-filling and partial-eject conditions. A 25-mm Medtronic Hall valve was installed in the mitral position of the EHTAH. Cavitation bubbles were concentrated on the valve stop; the major cause of these cavitation bubbles was determined to be squeeze flow. The valve-closing velocity was found to be proportional to increases in the LDP slope and the stroke volume of the left blood pump. The cavitation intensity and the cavitation event rate increased with increases in the stroke volume of the EHTAH. A consistent correlation was observed between the valve-closing velocity and the cavitation intensity. The LDP slope of the EHTAH may play an important role in estimating the mechanical heart valve cavitation intensity.
机译:这项研究的目的是建立一种估计电动液压全人工心脏(EHTAH)中的体外机械心脏瓣膜空化的方法。 EHTAH的左驱动压力(LDP)斜率的变化用作空化强度的指标。通过改变EHTAH的冲程体积来控制LDP斜率。冲程量从完全填充和完全弹出更改为部分填充和部分弹出条件。在EHTAH的二尖角位置安装了一个25毫米Medtronic霍尔阀。空化气泡集中在阀塞上。确定这些空化气泡的主要原因是挤压流动。发现阀门的关闭速度与LDP斜率和左血泵的搏动量的增加成比例。空化强度和空化事件率随着EHTAH的搏动量的增加而增加。在气门关闭速度和空化强度之间观察到一致的相关性。 EHTAH的LDP斜率可能在估计机械性心脏瓣膜空化强度中起重要作用。

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