Exercise hemodynamics during extended continuous flow left ventricular assist device support: the response of systemic cardiovascular parameters and pump performance.

Jerson Martina; Nicolaas Jonge; Marcel Rutten; J Hans Kirkels; Corinne Kl?pping; Ben Rodermans; Eveline Sukkel; Nelienke Hulstein; Bas Mol; Jaap Lahpor

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Exercise hemodynamics during extended continuous flow left ventricular assist device support: the response of systemic cardiovascular parameters and pump performance.

机译：左心室辅助装置支持持续连续流动时的运动血流动力学：全身心血管参数和泵性能的反应。

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Patients on continuous flow left ventricular assist devices (cf-LVADs) are able to return to an active lifestyle and perform all sorts of physical activities. This study aims to evaluate exercise hemodynamics in patients with a HeartMate II cf-LVAD (HM II). Thirty (30) patients underwent a bicycle exercise test. Along with exercise capacity, systemic cardiovascular responses and pump performance were evaluated at 6 and 12 months after HM II implantation. From rest to maximum exercise, heart rate increased from 87?±?14 to 140?±?32 beats/minute (bpm) (P?

机译：连续流左心室辅助装置（cf-LVAD）的患者能够恢复活跃的生活方式并进行各种体育锻炼。这项研究旨在评估HeartMate II cf-LVAD（HM II）患者的运动血液动力学。 30（30）名患者接受了自行车运动测试。 HM II植入后6个月和12个月，评估了运动能力，全身心血管反应和泵的性能。从休息到最大运动，心率从87？±？14增至140？±？32次/分钟（bpm）（P 0.01），而收缩压从93？±？12增至116?。 ±±21mm·mmHg（P ＜0.01）。总心输出量（TCO）从4.1？±？1.1增加到8.5？±？2.8？L / min（P 0.01），而泵流量增加较少，从5.1？±？0.7到6.4？±？0.6？L /min(P≤0.01）。全身血管阻力（SVR）从1776？±？750降至1013？±？383 dynes.s / cm（5）（P 0.001），并且与TCO的相关性最强（r？=？-0.72; P ＜0.01。运动能力受年龄的影响，而男性的血压明显高于女性。 HM II植入后6个月和12个月，运动能力保持稳定，正常受试者的年龄和性别校正后的预期最大VO2 max为51％？±？13％和52％？±？13％。总之，运动中HM II的泵流量可能部分影响TCO，而SVR是TCO的最强决定因素。

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《Artificial Organs》 |2013年第9期|共9页
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Jerson Martina; Nicolaas Jonge; Marcel Rutten; J Hans Kirkels; Corinne Kl?pping; Ben Rodermans; Eveline Sukkel; Nelienke Hulstein; Bas Mol; Jaap Lahpor;
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1. Exercise hemodynamics during extended continuous flow left ventricular assist device support: the response of systemic cardiovascular parameters and pump performance. [J] . Jerson Martina, Nicolaas Jonge, Marcel Rutten, Artificial Organs . 2013,第9期

机译：左心室辅助装置支持持续连续流动时的运动血流动力学：全身心血管参数和泵性能的反应。
2. Effect of exercise and pump speed modulation on invasive hemodynamics in patients with centrifugal continuous-flow left ventricular assist devices [J] . Muthiah Kavitha, Robson Desiree, Prichard Roslyn, The Journal of heart and lung transplantation: the official publication of the International Society for Heart Transplantation . 2015,第4期

机译：运动和泵速调制对离心式连续流左心室辅助装置患者侵入性血流动力学的影响
3. Cellular and Hemodynamics Responses of Failing Myocardium to Continuous Flow Mechanical Circulatory Support Using the DeBakey-Noon Left Ventricular Assist Device: a Comparative Analysis With Pulsatile-Type Devices. [J] . Thohan V, Nagueh SF, Koerner MM, The Journal of heart and lung transplantation: the official publication of the International Society for Heart Transplantation . 2005,第5期

机译：使用DeBakey-Noon左心室辅助装置对持续衰竭的机械循环支持的心肌衰竭的细胞和血液动力学响应：与搏动型装置的比较分析。
4. Adaptive Pump Speed Algorithms to Improve Exercise Capacity in Patients Supported with a Left-Ventricular Assist Device [C] . Thomas SCHMIDT, Nils REISS, Ezin DENIZ, eHealth Conference . 2017

机译：自适应泵速算法以提高左心室辅助装置支持的患者的运动能力
5. Partial vs. full support of the heart with a continuous-flow left ventricular assist device: Implications for myocardial recovery [D] . Bartoli, Carlo Renato G. 2011

机译：部分与心脏的全部支持与连续流动的左心室辅助装置：对心肌恢复的影响
6. Corrigendum to Evaluating the Hemodynamical Response of a Cardiovascular System under Support of a Continuous Flow Left Ventricular Assist Device via Numerical Modeling and Simulations [O] . Selim Bozkurt, Koray K. Safak 2019

机译：有关通过数值建模和仿真评估在持续流动的左心室辅助装置支持下的心血管系统的血流动力学响应的勘误
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Exercise hemodynamics during extended continuous flow left ventricular assist device support: the response of systemic cardiovascular parameters and pump performance.

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