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Dialysate and blood temperature during hemodialysis: comparing isothermic dialysis with a single-pass batch system.

机译:血液透析期间的透析液和血液温度:将等温透析与单次通过批次系统进行比较。

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The Genius is a convenient single-pass batch hemodialysis system. Dialysate is heated during the preparation phase. Once the container is filled at one of the three available starting temperatures, dialysate cools spontaneously. As dialysate temperature plays an important role in hemodynamic stability, knowledge of the instantaneous dialysate temperature is important. We documented the evolution of dialysate temperature during Genius dialysis with dialysate prepared at two different temperatures (low and medium) as well as its effect on blood temperature and hemodynamic stability. Genius dialysis was compared to isothermic dialysis obtained by a module programmed to obtain a constant blood temperature. With Genius, dialysate temperature progressively decreased from 36.3 (low) and 37.6 degrees C (medium) in the beginning to 34.4 and 35.3 degrees C at the end of the session, both following first-order kinetics. During isothermic dialysis, dialysate cooled from 37.3 to 35.4 degrees C, being warmer than with Genius low. Blood temperature decreased during dialysis with Genius low, from 36.4 to 36.2 degrees C, whereas with medium temperature, blood temperature initially rose from 36.4 degrees C at 15 min to 36.5 and 36.6 degrees C at 30 and 60 min, respectively, followed by a decrease from 180 min onward, to 36.4 degrees C at the end. During isothermic dialysis, blood temperature remained stable, as expected. Blood pressure decreased during all three schedules, with the highest value at 15 min during isothermic dialysis, and at the end of the session, the lowest value with isothermic dialysis.
机译:Genius是一种方便的单次批量血液透析系统。在准备阶段将透析液加热。在三个可用起始温度之一中填充容器后,透析液会自发冷却。由于透析液温度在血液动力学稳定性中起着重要作用,因此有关瞬时透析液温度的知识很重要。我们记录了Genius透析过程中透析液温度的演变,透析液在两种不同的温度(低和中)下制备,以及其对血压和血液动力学稳定性的影响。将天才透析与通过编程以获得恒定血液温度的模块获得的等温透析进行比较。使用Genius时,透析液温度从一开始的36.3(低)和37.6摄氏度(中)逐渐降低到会话结束时的34.4和35.3摄氏度,均遵循一阶动力学。在等温渗析过程中,透析液从37.3摄氏度冷却到35.4摄氏度,比Genius低温时的温度更高。在Genius较低的情况下,透析过程中的血液温度从36.4摄氏度降低到36.2摄氏度,而在中等温度下,血液温度最初从15分钟的36.4摄氏度分别升高到30分钟和60分钟的36.5摄氏度和36.6摄氏度,然后降低从180分钟开始,到最后36.4摄氏度。在等温透析过程中,血液温度保持稳定,符合预期。血压在所有三个时间表中均下降,等温渗析在15分钟时最高,而在疗程结束时,等渗渗析时最低。

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