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首页> 外文期刊>Artificial Organs >In Vivo Evaluation of Zirconia Ceramic in the DexAide Right Ventricular Assist Device Journal Bearing.
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In Vivo Evaluation of Zirconia Ceramic in the DexAide Right Ventricular Assist Device Journal Bearing.

机译：DexAide右心室辅助装置轴颈轴承中氧化锆陶瓷的体内评估。

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摘要

Zirconia is a ceramic with material properties ideal for journal bearing applications. The purpose of this study was to evaluate the use of zirconium oxide (zirconia) as a blood journal bearing material in the DexAide right ventricular assist device. Zirconia ceramic was used instead of titanium to manufacture the DexAide stator housing without changing the stator geometry or the remaining pump hardware components. Pump hydraulic performance, journal bearing reliability, biocompatibility, and motor efficiency data of the zirconia stator were evaluated in six chronic bovine experiments for 14-91 days and compared with data from chronic experiments using the titanium stator. Pump performance data including average in vivo pump flows and speeds using a zirconia stator showed no statistically significant difference to the average values for 16 prior titanium stator in vivo studies, with the exception of a 19% reduction in power consumption. Indices of hemolysis were comparable for both stator types. Results of coagulation assays and platelet aggregation tests for the zirconia stator implants showed no device-induced increase in platelet activation. Postexplant evaluation of the zirconia journal bearing surfaces showed no biologic deposition in any of the implants. In conclusion, zirconia ceramic can be used as a hemocompatible material to improve motor efficiency while maintaining hydraulic performance in a blood journal bearing application.
机译：氧化锆是一种陶瓷材料，其材料特性非常适合轴颈轴承应用。这项研究的目的是评估在DexAide右心室辅助设备中氧化锆（氧化锆）作为血液日志轴承材料的用途。使用氧化锆陶瓷代替钛来制造DexAide定子壳体，而无需更改定子几何形状或其余的泵硬件组件。在六个14-91天的长期牛实验中评估了氧化锆定子的泵液压性能，轴颈轴承可靠性，生物相容性和电机效率数据，并与使用钛定子的长期实验数据进行了比较。包括平均体内泵流量和使用氧化锆定子的转速在内的泵性能数据显示，与16项先前的钛定子体内研究的平均值相比，没有统计学上的显着差异，但功耗降低了19％。两种定子类型的溶血指数均相当。氧化锆定子植入物的凝结测定和血小板凝集试验结果表明，装置激活的血小板活化没有增加。氧化锆轴颈轴承表面的植入后评估表明，任何植入物中均无生物沉积。总之，氧化锆陶瓷可以用作血液相容性材料，以提高电机效率，同时在血液轴颈轴承应用中保持液压性能。

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