• 主题
高级搜索  >
历史搜索 清空历史
首页> 外文期刊>Artificial Organs >Simultaneous automatic control of oxygen and carbon dioxide blood gases during cardiopulmonary bypass.
【24h】

Simultaneous automatic control of oxygen and carbon dioxide blood gases during cardiopulmonary bypass.

机译：在体外循环过程中同时自动控制氧气和二氧化碳血气。

获取原文
获取原文并翻译 | 示例
           
页面导航
  • 摘要
  • 著录项
  • 相似文献
  • 相关主题

摘要

In this work an automatic control strategy is presented for the simultaneous control of oxygen and carbon dioxide blood gas partial pressures to be used during cardiopulmonary bypass surgery with heart-lung machine support. As the exchange of blood gases in the artificial extracorporeal lung is a highly nonlinear process comprising varying time delays, uncertainties, and time-varying parameters, it is currently being controlled manually by specially trained perfusionist staff. The new control strategy includes a feedback linearization routine with augmented time-delay compensation and two external linear gain-scheduled controllers, for partial oxygen and carbon dioxide pressures. The controllers were robustly tuned and tested in simulations with a detailed artificial lung (oxygenator) model in cardiopulmonary bypass conditions. Furthermore, the controllers were implemented in an ex vivo experiment using fresh porcine blood as a substitute fluid and a special deoxygenation technique to simulate a patient undergoing cardiopulmonary bypass. Both controllers showed robust stability during the experiments and a good disturbance rejection to extracorporeal blood flow changes. This automatic control strategy is proposed to improve patient's safety by fast control reference tracking and good disturbance rejection under varying conditions.
机译：在这项工作中，提出了一种自动控制策略，用于同时控制带有心肺机支架的心肺分流手术中使用的氧气和二氧化碳血气分压。由于人工体外肺中血液气体的交换是高度非线性的过程，包括不同的时间延迟，不确定性和随时间变化的参数，因此，目前由经过专门培训的灌注师人员对其进行手动控制。新的控制策略包括带有增加的延时补偿的反馈线性化程序和两个外部线性增益预定控制器，用于部分氧气和二氧化碳压力。在详细的人工肺（氧合器）模型中，在体外循环条件下对控制器进行了稳健的调试和仿真测试。此外，在体外实验中使用新鲜的猪血作为替代液并采用特殊的脱氧技术模拟体外循环的患者，实现了控制器。两种控制器在实验过程中均显示出稳定的稳定性，并对体外血流变化具有良好的抑制干扰性。提出了这种自动控制策略，以通过在不同条件下进行快速控制参考跟踪和良好的干扰抑制来提高患者的安全性。

著录项

相似文献

  • 外文文献
  • 中文文献
  • 专利
获取原文

客服邮箱：kefu@zhangqiaokeyan.com

京公网安备：11010802029741号 ICP备案号：京ICP备15016152号-6 六维联合信息科技 (北京) 有限公司©版权所有

  • 客服微信

  • 服务号