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Aortic root physiology late after a 'perfect' ross operation: magnetic resonance imaging study of three operative techniques.

机译:一次“完美”的玫瑰手术后的主动脉根生理:磁共振成像研究三种手术技术。

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In order to define physiological properties of the autograft root, magnetic resonance imaging (MRI) findings relative to three different operative techniques were compared with those of control subjects. Twenty-three patients, 18/5 M/F, aged 32 +/- 9 years, underwent MRI assessment of the aortic root. Patients with normally functioning autograft valve and at least 4 years of follow-up (average 5.6 +/- 1.9, range 4-10 years) were selected for each technique: six subcoronary (Group 1), nine inclusion (Group 2), and eight freestanding root (Group 3). Results were compared among patient groups and with seven control subjects, 6/1 M/F, aged 30 +/- 2 years (P = ns). Morphological and functional properties were defined using transverse and paracoronal views, during systole and diastole. Mean aortic size in each group was greater than control, except for the LV-aortic junction and the sinus of Valsalva in Group 1 (26 +/- 5 vs. 23 +/- 3 mm, P = 0.2 and 33 +/- 6 vs. 30 +/- 5 mm, P = 0.3). Aortic valve plane rotation (P = 0.02) and root dilatation (P = 0.02) were more common in Group 3. Altered valve opening dynamics and asymmetrical aortic flow profile were also more common in Group 2 (P = 0.03) and Group 3 (P = 0.04). Distensibility was significantly reduced at sinus level in Group 2 and 3 compared with control (4.1 +/- 3.5% and 3.6 +/- 4.4% vs. 9.0 +/- 4.7%, P = 0.03). Asymmetrical aortic flow profile was more common in patients with aortic dilatation (P = 0.05) and with severely reduced (<4%) root elasticity (P = 0.06). Among the three techniques, only subcoronary grafting allows preservation of physiological autograft valve dynamics, aortic flow and distensibility, at all root levels, late after operation. These findings may have relevant implications in the selection of the ideal Ross technique.
机译:为了定义自体移植根的生理特性,将相对于三种不同手术技术的磁共振成像(MRI)结果与对照对象进行了比较。 23名18/5 M / F的患者,年龄32 +/- 9岁,接受了主动脉根的MRI评估。为每种技术选择具有正常功能的自体瓣膜并且至少随访4年(平均5.6 +/- 1.9,范围4-10年)的患者:六个冠状动脉(第1组),九个包涵物(第2组)和八个独立根(第3组)。比较了患者组和7个对照组(6/1 M / F,年龄30 +/- 2岁)的结果(P = ns)。在收缩期和舒张期使用横断面和冠状旁观确定形态和功能特性。除第1组的LV-主动脉交界处和Valsalva窦外,各组的平均主动脉大小均大于对照组(26 +/- 5 vs. 23 +/- 3 mm,P = 0.2和33 +/- 6与30 +/- 5毫米,P = 0.3)。在第3组中,主动脉瓣平面旋转(P = 0.02)和根部扩张(P = 0.02)在第3组中更常见。在第2组(P = 0.03)和第3组(P中,改变的瓣膜开度动力学和不对称主动脉血流分布也更为常见。 = 0.04)。与对照组相比,第2组和第3组在鼻窦水平的可扩张性显着降低(4.1 +/- 3.5%和3.6 +/- 4.4%与9.0 +/- 4.7%,P = 0.03)。主动脉扩张(P = 0.05)且根部弹性严重降低(<4%)的患者(P = 0.06),主动脉血流不对称更为常见。在这三种技术中,仅次冠状动脉移植可在术后后期在所有根部水平上保留生理性自体移植瓣膜动力学,主动脉血流和扩张性。这些发现可能对理想的Ross技术的选择具有重要的意义。

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