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首页> 外文期刊>Artificial Organs >Assessment of health-related quality of life in patients treated with hemodialysis in Serbia: influence of comorbidity, age, and income.
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Assessment of health-related quality of life in patients treated with hemodialysis in Serbia: influence of comorbidity, age, and income.

机译：塞尔维亚血液透析治疗患者的健康相关生活质量评估：合并症，年龄和收入的影响。

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The importance of measuring health-related quality of life (HRQoL) in patients on maintenance hemodialysis (HD) is being increasingly recognized, but few studies, especially from the Balkan region, have addressed this issue. The aims of this study were (i) to evaluate HRQoL in an outpatient university-affiliated dialysis facility in South Serbia; (ii) to determine the effects of age, presence of comorbidity, primary kidney disease, dose of HD, and family income; and (iii) to make comparisons of the HRQoL in Serbian patients on chronic HD with that reported by others previously. The study enrolled 192 patients on HD for more than 3 months. Comorbidity was assessed using the index of coexistent diseases (ICED), including two subindexes: index of disease severity (IDS) and index of physical impairment (IPI). Patient's self-assessment of HRQoL was measured by the 36-item short form health survey questionnaire (SF-36), encompassing eight summary scales and two summary dimensions. Ten of the baseline variables had significant associations with parameters of HRQoL. Fitting these variables in linear regression models resulted in 41.9% variance for physical dimension of HRQoL (physical component summary score [PCS]), and 32.5% for mental dimension of HRQoL (mental component summary score [MCS]). However, statistically significant effect had only IDS, IPI, and age for PCS, and income of patients for MCS. We found that an increase in IDS score for one unit is associated with a decrease of PCS by 13.2%, and SF-36 score (total quality of life) by 15.2%. The increase of IPI score by one unit decreases PCS by 16.1% and SF-36 score by 17.5%. A 5-year increase in age is associated with a decrease of PCS by 3.1%, and SF-36 score by 3.8%. The monthly income increase of 10 euros per family member increases MCS by 5.2% and SF-36 score by 3.0%. HRQoL in patients on HD was found markedly impaired. Comorbid conditions have negative and statistically significant correlation with parameters of HRQoL, and could explain poor HRQoL to a remarkable extent. Older age and poor income substantially reduce HRQoL in HD patients.
机译：维持性血液透析（HD）患者测量与健康相关的生活质量（HRQoL）的重要性已得到越来越多的认识，但是很少有研究，尤其是来自巴尔干地区的研究，已经解决了这个问题。这项研究的目的是（i）在南塞尔维亚的一家大学附属门诊透析设施中评估HRQoL; （ii）确定年龄，合并症，原发性肾脏疾病，HD剂量和家庭收入的影响; （iii）将塞尔维亚慢性肾脏病患者的HRQoL与先前其他人的报告进行比较。该研究招募了192例接受HD治疗超过3个月的患者。使用共存疾病指数（ICED）评估合并症，包括两个子指数：疾病严重程度指数（IDS）和身体损害指数（IPI）。患者的HRQoL自我评估是通过36个项目的简短健康调查问卷（SF-36）进行的，其中包括八个汇总量表和两个汇总量表。基线变量中的十个与HRQoL参数有显着关联。在线性回归模型中拟合这些变量会导致HRQoL的身体尺寸（身体成分总评分[PCS]）有41.9％的变异，而HRQoL的心理尺寸（精神成分总得分[MCS]）有32.5％的变异。然而，统计学上显着的影响仅对PCS具有IDS，IPI和年龄，对MCS具有患者收入。我们发现，一个单位的IDS分数增加与PCS减少13.2％和SF-36分数（总生活质量）减少15.2％相关。 IPI分数增加1个单位会使PCS减少16.1％，SF-36分数减少17.5％。年龄增加5年会导致PCS下降3.1％，SF-36得分下降3.8％。每个家庭成员每月增加10欧元的收入可使MCS增长5.2％，SF-36得分提高3.0％。发现HD患者的HRQoL明显受损。合并症与HRQoL的参数具有负相关且在统计上具有显着相关性，并且可以在很大程度上解释HRQoL较差。年龄大和收入差会大大降低HD患者的HRQoL。

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