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Evaluation of a Spiral Groove Geometry for Improvement of Hemolysis Level in a Hydrodynamically Levitated Centrifugal Blood Pump

机译:螺旋槽几何形状的评估,以改善水动力悬浮离心血泵的溶血水平

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The purpose of this study is to evaluate a spiral groove geometry for a thrust bearing to improve the hemolysis level in a hydrodynamically levitated centrifugal blood pump. We compared three geometric models: (i) the groove width is the same as the ridge width at any given polar coordinate (conventional model); (ii) the groove width contracts inward from 9.7 to 0.5mm (contraction model); and (iii) the groove width expands inward from 0.5 to 4.2mm (expansion model). To evaluate the hemolysis level, an impeller levitation performance test and in vitro hemolysis test were conducted using a mock circulation loop. In these tests, the driving conditions were set at a pressure head of 200mmHg and a flow rate of 4.0L/min. As a result of the impeller levitation performance test, the bottom bearing gaps of the contraction and conventional models were 88 and 25m, respectively. The impeller of the expansion model touched the bottom housing. In the hemolysis test, the relative normalized index of hemolysis (NIH) ratios of the contraction model in comparison with BPX-80 and HPM-15 were 0.6 and 0.9, respectively. In contrast, the relative NIH ratios of the conventional model in comparison with BPX-80 and HPM-15 were 9.6 and 13.7, respectively. We confirmed that the contraction model achieved a large bearing gap and improved the hemolysis level in a hydrodynamically levitated centrifugal blood pump.
机译:这项研究的目的是评估推力轴承的螺旋槽几何形状,以改善流体动力悬浮离心血泵的溶血水平。我们比较了三种几何模型:(i)在任何给定的极坐标下,槽宽与脊宽相同(常规模型); (ii)凹槽宽度从9.7mm缩小到0.5mm(收缩模型); (iii)凹槽宽度从0.5mm向内扩大至4.2mm(扩展模型)。为了评估溶血水平,使用模拟循环回路进行了叶轮悬浮性能测试和体外溶血测试。在这些测试中,行驶条件设定为200mmHg的压头和4.0L / min的流速。叶轮悬浮性能测试的结果是,收缩模型和常规模型的底部轴承间隙分别为88m和25m。扩展型号的叶轮触及底部外壳。在溶血试验中,与BPX-80和HPM-15相比,收缩模型的相对溶血指数(NIH)比率分别为0.6和0.9。相反,与BPX-80和HPM-15相比,常规模型的相对NIH比率分别为9.6和13.7。我们确认,收缩模型实现了较大的轴承间隙,并改善了流体动力悬浮离心血泵的溶血水平。

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