Performance characterization of a rotary centrifugal left ventricular assist device with magnetic suspension.

Jahanmir S; Hunsberger AZ; Heshmat H; Tomaszewski MJ; Walton JF; Weiss WJ; Lukic B; Pae WE; Zapanta CM; Khalapyan TZ

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Performance characterization of a rotary centrifugal left ventricular assist device with magnetic suspension.

机译：具有磁性悬架的旋转离心式左心室辅助设备的性能表征。

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摘要

The MiTiHeart (MiTiHeart Corporation, Gaithersburg, MD, USA) left ventricular assist device (LVAD), a third-generation blood pump, is being developed for destination therapy for adult heart failure patients of small to medium frame that are not being served by present pulsatile devices. The pump design is based on a novel, patented, hybrid passive/active magnetic bearing system with backup hydrodynamic thrust bearing and exhibits low power loss, low vibration, and low hemolysis. Performance of the titanium alloy prototype was evaluated in a series of in vitro tests with blood analogue to map out the performance envelop of the pump. The LVAD prototype was implanted in a calf animal model, and the in vivo pump performance was evaluated. The animal's native heart imparted a strong pulsatility to the flow rate. These tests confirmed the efficacy of the MiTiHeart LVAD design and confirmed that the pulsatility does not adversely affect the pump performance.

机译：MiTiHeart（MiTiHeart Corporation，Gaithersburg，MD，USA）左心室辅助装置（LVAD）是第三代血泵，正在开发中，用于目前尚无法提供服务的中小型成人心力衰竭患者的目的地治疗搏动性装置。该泵的设计基于具有备用液压动力推力轴承的新型，专利的混合式被动/主动磁轴承系统，并且功率损耗低，振动小，溶血少。钛合金原型的性能在一系列血液模拟体外测试中进行了评估，以绘制出泵的性能曲线。 LVAD原型植入小牛动物模型，并评估体内泵的性能。动物的自然心脏使流速具有很强的脉动性。这些测试证实了MiTiHeart LVAD设计的功效，并证实了脉动性不会对泵的性能产生不利影响。

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《Artificial Organs》 |2008年第5期|共10页
作者
Jahanmir S; Hunsberger AZ; Heshmat H; Tomaszewski MJ; Walton JF; Weiss WJ; Lukic B; Pae WE; Zapanta CM; Khalapyan TZ;
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正文语种 eng
中图分类医用一般科学;外科手术学;
关键词
Performance; Pump; NOS; Magnetism; Suspensions; 悬液;

机译：Performance;Pump;NOS;Magnetism;Suspensions;悬液;

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1. Performance characterization of a rotary centrifugal left ventricular assist device with magnetic suspension. [J] . Jahanmir S, Hunsberger AZ, Heshmat H, Artificial Organs . 2008,第5期

机译：具有磁性悬架的旋转离心式左心室辅助设备的性能表征。
2. A mock circulatory system to assess the performance of continuous-flow left ventricular assist devices (LVADs): Does axial flow unload better than centrifugal LVAD? [J] . SénageT., FévrierD., MichelM., ASAIO journal . 2014,第2期

机译：用于评估连续流左心室辅助设备（LVAD）性能的模拟循环系统：轴向流的卸载是否比离心LVAD更好？
3. Cessation of anti-coagulation for bleeding and subsequent thrombosis events with a fully magnetically levitated centrifugal left ventricular assist device [J] . Gosev Igor, Ayers Brian, Wood Katherine, The Journal of heart and lung transplantation: the official publication of the International Society for Heart Transplantation . 2019,第7期

机译：用于出血的抗凝固和随后血栓形成事件的抗凝血，具有完全悬浮的离心左心室辅助装置
4. A DYNAMICAL STATE SPACE REPRESENTATION AND PERFORMANCE ANALYSIS OF A FEEDBACK CONTROLLED ROTARY LEFT VENTRICULAR ASSIST DEVICE [C] . Antonio Ferreira, Shaohui Chen, David G. Galati, DSC-vol.74-1; American Society of Mechanical Engineers(ASME) International Mechanical Engineering Congress and Exposition; 20051105-11; Orlando,FL(US) . 2005

机译：反馈控制左心室辅助装置的动力学状态空间表示及性能分析
5. Hydrodynamics of axial-flow and centrifugal-flow left ventricular assist devices [D] . Stanfield, James Ryan 2012

机译：轴流和离心流左心室辅助装置的流体力学
6. Development of tricuspid regurgitation and right ventricular performance after implantation of centrifugal left ventricular assist devices [O] . Johanna Mulzer, Hristo Krastev, Christoph Hoermandinger, 2021

机译：植入离心左心室辅助装置后三尖瓣流动和右心室性能的发展
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机译：识别用作左心室辅助装置的可植入旋转血泵中生理上显着的泵送状态转变：体内研究。

Performance characterization of a rotary centrifugal left ventricular assist device with magnetic suspension.

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