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首页> 外文期刊>Artificial Organs >Influence of Oxynitrided Surface in the Production of a Less Susceptible Titanium Surface to Skin-Borne Bacterial Adhesion
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Influence of Oxynitrided Surface in the Production of a Less Susceptible Titanium Surface to Skin-Borne Bacterial Adhesion

机译：氧氮化表面对难感性钛表面的产生对皮肤细菌粘附的影响

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摘要

There is a growing quest for an ideal biomaterial that shows appropriate cellular response and is not susceptible to microbial adhesion. In this study, commercial grade II titanium was submitted to RF/DC plasma surface modification at 2.2 mbar, using gas mixtures of argon, nitrogen, and oxygen at proportions 4: 1: 2 and 4: 1: 3. The surfaces were physically and chemically characterized. In order to evaluate bacterial response, the surfaces were exposed to Staphylococcus epidermidis. Oxynitrided samples, although having a higher roughness as compared with untreated samples, exhibited lower bacterial growth. This observation is probably due to the formation of different crystalline phases of nitrides and oxides caused by plasma treatment. The surface with highest contact angle and highest surface tension showed lower bacterial adhesion. These results were confirmed by scanning electron microscopy. The role of nitrogen in reducing bacterial adhesion is clear when this material is compared with untreated titanium, on which only an oxide film is present.
机译：人们越来越需要一种理想的生物材料，该材料应显示出适当的细胞反应，并且不易受到微生物的粘附。在这项研究中，使用等级为4：1：1：2和4：1：3的氩气，氮气和氧气的混合气体，对商用II级钛进行了2.2 mbar的RF / DC等离子体表面改性。化学表征。为了评估细菌反应，将表面暴露于表皮葡萄球菌。尽管与未经处理的样品相比，经氧氮化的样品具有更高的粗糙度，但其细菌生长却较低。该观察结果可能是由于等离子体处理引起的氮化物和氧化物的不同晶相的形成。具有最高接触角和最高表面张力的表面显示出较低的细菌粘附性。这些结果通过扫描电子显微镜证实。与未处理的钛（仅存在氧化膜）相比，氮在减少细菌粘附方面的作用显而易见。

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