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首页> 外文期刊>Asia-Pacific journal of public health >Economic evaluation of the national immunization program of rotavirus vaccination for children in Korea
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Economic evaluation of the national immunization program of rotavirus vaccination for children in Korea

机译：韩国儿童轮状病毒疫苗国家免疫计划的经济评估

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The authors assessed the cost-effectiveness of rotavirus vaccination to develop an evidence-based national immunization program in Korea. A Markov model was constructed to compare the costs and clinical outcomes of vaccination versus no vaccination. The birth cohort of 493189 infants in 2007 was followed until the age of 5 years. Korea-specific data for epidemiological characteristics and economic burden of rotavirus diarrhea were used for the modeled estimation. Efficacy of RotaTeq? was based on a recent clinical trial. Rotavirus vaccination would prevent 181238 symptomatic cases (reduction rate = 63.2%) over 5 years after birth. From the societal perspective, at a vaccination cost of 100000 Korean won (KW; 1 US$ ≈ 1200 KW) per dose, universal vaccination would cost 375 620 KW per case averted. The breakeven price of vaccine was 56061 KW. Rotavirus vaccination would reduce the burden of the disease substantially and be a cost-effective strategy to prevent rotavirus diarrhea in Korea.
机译：作者评估了轮状病毒疫苗接种在韩国制定基于证据的国家免疫计划的成本效益。建立了马尔可夫模型以比较疫苗接种与不接种疫苗的成本和临床结果。随访了2007年的493189名婴儿的出生队列，直到5岁为止。轮状病毒性腹泻的流行病学特征和经济负担的韩国特定数据用于模型估计。 RotaTeq的功效？基于最近的一项临床试验。轮状病毒疫苗接种可在出生后5年内预防181238例有症状的病例（减少率= 63.2％）。从社会角度来看，每剂疫苗接种费用为100000韩元（KW; 1美元≈1200 KW），每例疫苗的平均接种费用为375620 KW。疫苗的收支平衡价格为56061千瓦。轮状病毒疫苗接种将大大减轻该疾病的负担，并且是在韩国预防轮状病毒腹泻的一种划算的策略。

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